Synthesis of new functionalized derivatives of 1,2,4-triazolo[4′,3′:2,3][1,2,4]triazino[5,6-b]indole

被引：12

作者：

Gomha, Sobhi M. ^{[1
]}

Abdel-Aziz, Hatem A. ^{[2
]}

机构：

[1] Cairo Univ, Fac Sci, Dept Chem, Giza, Egypt

[2] King Saud Univ, Coll Pharm, Dept Pharmaceut Chem, Riyadh 11451, Saudi Arabia

来源：

JOURNAL OF THE SERBIAN CHEMICAL SOCIETY | 2013年 / 78卷 / 08期

关键词：

hydrazonoyl halides; 1,2,4-triazino[5,6-b]indole-3-thione; hydrazonothioates; CHEMOTHERAPEUTIC-AGENTS; INHIBITION; MECHANISM;

D O I：

10.2298/JSC120914013G

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

New functionalized 1,2,4-triazolo[4',3':2,3][1,2,4]triazino[5,6-b]indole derivatives were synthesized via reaction of the hydrazonoyl halides with 2,4-dihydro-3H-1,2,4-triazino[5,6-b]indole-3-thione or its 3-methylthio derivative. The mechanism and the regioselectivity of the studied reactions are discussed.

引用

页码：1119 / 1125

页数：7

共 50 条

[41] TFA-catalyzed Q-Tube Reactor-Assisted Strategy for the Synthesis of Pyrido[1,2-b][1,2,4]triazine and Pyrido[1′,2′:2,3][1,2,4]triazino[5,6-b]indole Derivatives
Ibrahim, Hamada Mohamed
Behbehani, Haider
ACS OMEGA, 2021, 6 (24): : 16086 - 16099
[42] First synthesis of tert-butyl-substituted [1,2,4]triazino[5,6-b]indole-3-thiols and indolo[2,3-b]quinoxalines
Lv, Mingyue
Zheng, Hongmei
Li, Yang
Gao, Wentao
RESEARCH ON CHEMICAL INTERMEDIATES, 2015, 41 (10) : 6927 - 6939
[43] SYNTHESIS OF 1,2,4-TRIAZOLO[3,4-F]-1,2,4-TRIAZINO[4,5-A]INDOLES
HIREMATH, SP
SEKHAR, KR
SONAR, VN
PUROHIT, MG
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1990, 29 (04): : 372 - 375
[44] First synthesis of tert-butyl-substituted [1,2,4]triazino[5,6-b]indole-3-thiols and indolo[2,3-b]quinoxalines
Mingyue Lv
Hongmei Zheng
Yang Li
Wentao Gao
Research on Chemical Intermediates, 2015, 41 : 6927 - 6939
[45] CHEMISTRY OF 1,2,4-TRIAZINES .13. SYNTHESIS OF 1H-[1,2,4]TRIAZINO[5,6-E][1,3,4]THIADIAZINES AND 1,2,4-TRIAZOLO[4,3-D][1,2,4]TRIAZINES
NEUNHOEFFER, H
DOSTERT, M
HAMMANN, H
SYNTHESIS-STUTTGART, 1988, (10): : 778 - 782
[46] Synthesis, conformational analysis and antimicrobial activity of 10-benzyl-1,2,4-triazolo[4,3-b]1,2,4-triazino[5,6-b]indole acyclo C-nucleoside analogs
Nasr, Adel Z.
Keshk, Reda M.
Abdelrehim, El-Sayed M.
Sallam, Asmaa S.
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2024,
[47] Synthesis of new pyrido[4′,3′:4,5]thieno[2,3-d]-1,2,4-triazolo[3,4-c]pyrimidines and a 5,6-dihydro-1,2,4-triazolo[4",3":1′,2′]pyrido[4′,3′:4,5]thieno[2,3-d]-pyrimidine ring system
Ahmed, EK
Gohar, AMN
Ameen, MA
PHARMAZIE, 2000, 55 (01): : 31 - 34
[48] Convenient Synthesis 5H-[1,2,4]Triazine[5,6-b]indole-3-thiol Derivatives
Gao, Wentao
Lan, Shuai
Bairenqing, Zhuoma
Li, Yang
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2014, 34 (10) : 2106 - 2118
[49] A study of the synthesis and nonlinear optical properties of 3-substituted 5H-[1,2,4]triazolo[3′,4′:2,3] [1,3,4]thiadiazino[5,6-b]quinoxaline derivatives
Mahmoody, Miri
Khalafy, Jabbar
Baradarani, Mehdi M.
CHIMICA OGGI-CHEMISTRY TODAY, 2017, 35 (03) : 44 - 47
[50] FLUORINE CONTAINING BIOACTIVE HETEROCYCLES - INVESTIGATION OF THE REACTIONS OF FLUORINE CONTAINING 3-HYDRAZINO-5H-1,2,4-TRIAZINO[5,6-B]INDOLES WITH CARBON-DISULFIDE AND SYNTHESIS OF 2,3-DIHYDRO-1-THIOXO-1,2,4-TRIAZOLO[3,4-C]-1,2,4-TRIAZINO[5,6-B]INDOLES AS ANTIBACTERIAL AGENTS
JOSHI, KC
DANDIA, A
BAWEJA, S
JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 1989, 66 (8-10) : 690 - 693

← 1 2 3 4 5 →