Synthesis of new functionalized derivatives of 1,2,4-triazolo[4′,3′:2,3][1,2,4]triazino[5,6-b]indole

被引：12

作者：

Gomha, Sobhi M. ^{[1
]}

Abdel-Aziz, Hatem A. ^{[2
]}

机构：

[1] Cairo Univ, Fac Sci, Dept Chem, Giza, Egypt

[2] King Saud Univ, Coll Pharm, Dept Pharmaceut Chem, Riyadh 11451, Saudi Arabia

来源：

JOURNAL OF THE SERBIAN CHEMICAL SOCIETY | 2013年 / 78卷 / 08期

关键词：

hydrazonoyl halides; 1,2,4-triazino[5,6-b]indole-3-thione; hydrazonothioates; CHEMOTHERAPEUTIC-AGENTS; INHIBITION; MECHANISM;

D O I：

10.2298/JSC120914013G

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

New functionalized 1,2,4-triazolo[4',3':2,3][1,2,4]triazino[5,6-b]indole derivatives were synthesized via reaction of the hydrazonoyl halides with 2,4-dihydro-3H-1,2,4-triazino[5,6-b]indole-3-thione or its 3-methylthio derivative. The mechanism and the regioselectivity of the studied reactions are discussed.

引用

页码：1119 / 1125

页数：7

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