2,2-Bis(trifluoromethyl)-2,3-dihydro-1H-1,5-benzodiazepines

被引：1
|
作者：
Petko, K. I. [1 ]
Vorobey, V. M. [1 ]
Gutov, A. V. [1 ]
Chernega, A. N. [1 ]
机构：
[1] Natl Acad Sci Ukraine, Inst Organ Chem, UA-02660 Kiev, Ukraine
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2013年 / 49卷 / 08期
关键词：
1,5-benzodiazepines; hexafluoroacetone N-phenylimines; X-ray structural analysis;
D O I：
10.1007/s10593-013-1360-8
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A method for the cyclization of hexafluoroacetone N-phenylimine derivatives with the formation of benzodiazepine analogs containing trifluromethyl groups has been elaborated. The obtained compounds were characterized by the NMR and mass spectral analysis and by the data from X-ray structural analysis.
引用
收藏
页码：1172 / 1179
页数：8
相关论文
共 50 条
  • [41] Syntheses of benzimidazoles, quinoxalines and 3,3-dihydro-1H-1,5-benzodiazepines starting from o-phenylenediamine
    Cui, Y
    Tang, XB
    Shao, CX
    Li, JT
    Sun, WH
    CHINESE JOURNAL OF CHEMISTRY, 2005, 23 (05) : 589 - 595
  • [42] PREPARATION OF 2,3-DIHYDRO(1,5)BENZOTHIAZEPINES AND 2,3-DIHYDRO(1,5)BENZODIAZEPINES
    LANCELOT, JC
    LETOIS, B
    SATURNINO, C
    ROBBA, M
    SYNTHETIC COMMUNICATIONS, 1991, 21 (18-19) : 1901 - 1908
  • [43] Synthesis of 4-pyridyl-2,3-dihydro-1H-1,5-benzodiazepinones-2
    Bozhanov, VI
    Ivonin, SP
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 2002, (09): : 1255 - 1260
  • [44] SYNTHESIS OF 2,4-DIPHENYL-2,3-DIHYDRO-1H-1,5-BENZODIAZEPINE
    YAREMENKO, FG
    ORLOV, VD
    KOLOS, NN
    LAVRUSHIN, VF
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1979, (06): : 848 - 849
  • [45] CHLORODERIVATIVES OF 4-PHENYL-2,3-DIHYDRO-1H-1,5-BENZODIAZEPINONE-2
    SOLOMKO, ZF
    SHEREMET, VI
    KHMEL, MP
    AVRAMENKO, VI
    PROSHKINA, VN
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1982, (03): : 405 - 409
  • [46] FORMYLATION OF 4-ARYL-2,3-DIHYDRO-1H-1,5-BENZODIAZEPINONES-2
    SOLOMKO, ZF
    PROSHKINA, VN
    AVRAMENKO, VI
    PLASTUN, IA
    BOZHANOVA, NY
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1984, (09): : 1262 - 1265
  • [47] RECYCLIZATION OF 4-METHYL(PHENYL)-2,3-DIHYDRO-1H-1,5-BENZODIAZEPINONES-2
    GAPONOV, AA
    SOLOMKO, ZF
    BOZHANOVA, NY
    PANTYUKH, EI
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1989, (07): : 997 - 997
  • [48] Simultaneous reduction of the nitro group and the azide group in o-nitrophenylazide induced by the TiCl4/Sm system:: a novel synthesis of 2,3-dihydro-1H-1,5-benzodiazepines
    Zhong, WH
    Zhang, YM
    Chen, XY
    TETRAHEDRON LETTERS, 2001, 42 (01) : 73 - 75
  • [49] Synthesis of 2,4-diaryl-1,5-benzodiazepines and 2,4-diaryl-2,3-dihydro-1,5-benzothiazepines
    Padwad, M
    Ingle, VN
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 1999, 76 (03) : 161 - 162
  • [50] CONFORMATIONAL-ANALYSIS OF AROMATIC DERIVATIVES OF 2,3-DIHYDRO-1H-1,5-BENZODIAZEPINE
    ORLOV, VD
    KOLOS, NN
    ABRAMOV, AF
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1984, (12): : 1662 - 1666
12345