X-ray powder diffraction data for 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester, C27H28N4O5

被引：1
|
作者：
Wang, Qing [1 ]
Suo, Zi Li [1 ]
Zhang, Yong Kui [1 ]
Hou, Quan [1 ]
Li, Hui [1 ]
机构：
[1] Sichuan Univ, Coll Chem Engn, Chengdu 610065, Sichuan, Peoples R China
来源：
POWDER DIFFRACTION | 2017年 / 32卷 / 03期
关键词：
pharmaceutical intermediate; anticoagulant; apixaban; APIXABAN;
D O I：
10.1017/S0885715617000574
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7- tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester is an important intermediate in the synthesis of the anticoagulant, apixaban. X-ray powder diffraction data for this compound are reported [a = 14.101(4) angstrom, b = 10.105(6) angstrom, c = 9.532(7) angstrom, alpha = 72.774(1)degrees, beta = 97.356(3)degrees, gamma = 108.237(3)degrees, unit-cell volume V = 1231.45 angstrom(3), Z = 2, and space group P-1]. No detectable impurities were observed. (C) 2017 International Centre for Diffraction Data.
引用
收藏
页码：206 / 209
页数：4
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