X-ray powder diffraction data for 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester, C27H28N4O5

被引：1

作者：

Wang, Qing ^{[1
]}

Suo, Zi Li ^{[1
]}

Zhang, Yong Kui ^{[1
]}

Hou, Quan ^{[1
]}

Li, Hui ^{[1
]}

机构：

[1] Sichuan Univ, Coll Chem Engn, Chengdu 610065, Sichuan, Peoples R China

来源：

POWDER DIFFRACTION | 2017年 / 32卷 / 03期

关键词：

pharmaceutical intermediate; anticoagulant; apixaban; APIXABAN;

D O I：

10.1017/S0885715617000574

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7- tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester is an important intermediate in the synthesis of the anticoagulant, apixaban. X-ray powder diffraction data for this compound are reported [a = 14.101(4) angstrom, b = 10.105(6) angstrom, c = 9.532(7) angstrom, alpha = 72.774(1)degrees, beta = 97.356(3)degrees, gamma = 108.237(3)degrees, unit-cell volume V = 1231.45 angstrom(3), Z = 2, and space group P-1]. No detectable impurities were observed. (C) 2017 International Centre for Diffraction Data.

引用

页码：206 / 209

页数：4

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