Synthesis of tetrazole-substituted spirocyclic γ-lactams by one-pot azido-Ugi reaction-cyclization

被引：13
|
作者：
Stolyarenko, Vasiliy Yu [1 ]
Evdokimov, Anatoliy A. [1 ]
Shishkin, Vladimir I. [1 ]
机构：
[1] Moscow State Univ Radioelect Engn & Automat, Moscow 119454, Russia
来源：
MENDELEEV COMMUNICATIONS | 2013年 / 23卷 / 02期
关键词：
SOLUTION-PHASE PREPARATION; MULTICOMPONENT REACTIONS; CHEMISTRY;
D O I：
10.1016/j.mencom.2013.03.020
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
1-Ethoxycarbonyl-1-(2-oxoethyl)cycloalkanes in the azido-Ugi reaction with primary amines, isocyanides and TMS-N-3 afford 3-(tetrazol-5-yl)-2-azaspiro [4.n]alkan-1-ones.
引用
收藏
页码：108 / 109
页数：2
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