Synthesis of tetrazole-substituted spirocyclic γ-lactams by one-pot azido-Ugi reaction-cyclization

被引:13
|
作者
Stolyarenko, Vasiliy Yu [1 ]
Evdokimov, Anatoliy A. [1 ]
Shishkin, Vladimir I. [1 ]
机构
[1] Moscow State Univ Radioelect Engn & Automat, Moscow 119454, Russia
关键词
SOLUTION-PHASE PREPARATION; MULTICOMPONENT REACTIONS; CHEMISTRY;
D O I
10.1016/j.mencom.2013.03.020
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
1-Ethoxycarbonyl-1-(2-oxoethyl)cycloalkanes in the azido-Ugi reaction with primary amines, isocyanides and TMS-N-3 afford 3-(tetrazol-5-yl)-2-azaspiro [4.n]alkan-1-ones.
引用
收藏
页码:108 / 109
页数:2
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