(Z)-5-Fluoro-3-[(1H-pyrrol-2-yl)methylene]indolin-2-one

被引:4
|
作者
Zhang, Hongming [1 ]
Ankati, Haribabu [1 ]
Akubathini, Shashidhar Kumar [1 ]
Biehl, Ed [1 ]
机构
[1] So Methodist Univ, Dept Chem, Dallas, TX 75275 USA
关键词
KINASE;
D O I
10.1107/S1600536808040178
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
The title compound, C(13)H(9)FN(2)O, a potential neuroprotective agent, consists of an indolinone and a pyrrolyl unit [dihedral angle between the ring planes = 4.9 (1)degrees]. An intramolecular hydrogen bond between the carbonyl O atom and the NH group of pyrrole correlates with the Z arrangement of the substituents at the C=C bond. In the crystal, inversion dimers occur, linked by pairs of N-H center dot center dot center dot O bonds.
引用
收藏
页码:O8 / U1324
页数:9
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