Ceftriaxone-resistant, multidrug-resistant Neisseria gonorrhoeae with a novel mosaic penA-237.001 gene, France, June 2022

被引：15
|
作者：
Bercot, Beatrice [1 ,2 ,3 ]
Camelena, Francois [1 ,2 ,3 ]
Merimeche, Manel [1 ,2 ,3 ]
Jacobsson, Susanne [4 ]
Sbaa, Ghalia [2 ,3 ]
Mainardis, Mary [2 ,3 ]
Valin, Cyrille [5 ]
Molina, Jean-Michel [6 ,7 ]
Bebear, Cecile [8 ]
Chazelle, Emilie [9 ]
Lot, Florence [9 ]
Goliparian, Daniel [4 ]
Unemo, Magnus [4 ,10 ]
机构：
[1] Univ Paris Cite, IAME, INSERM, Paris, France
[2] St Louis Hosp, AP HP, Infect Agents Dept, Paris, France
[3] French Natl Reference Ctr Bacterial STIs, Associated Lab Gonococci, Paris, France
[4] Orebro Univ, Fac Med & Hlth, Dept Lab Med, Natl Reference Lab STIs,WHO Collaborating Ctr Gon, Orebro, Sweden
[5] Biogroup, Lab Anse, Lyon, France
[6] Hop St Louis, AP HP, Lariboisiere, Dept Malad Infect & Trop, Paris, France
[7] Univ Paris Cite, UMR S976, INSERM, Paris, France
[8] Univ Bordeaux, Bordeaux Univ Hosp, USC EA 3671, Mycoplasmal & Chlamydial Infect Humans,French Nat, Bordeaux, France
[9] French Natl Publ Hlth Agcy, Sante Publ France, St Maurice, France
[10] UCL, Inst Global Hlth, London, England
来源：
EUROSURVEILLANCE | 2022年 / 27卷 / 50期
关键词：
ANTIMICROBIAL RESISTANCE; ALLELE; STRAIN;
D O I：
10.2807/1560-7917.ES.2022.27.50.2200899
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
We report a ceftriaxone-resistant, multidrug-resistant urogenital gonorrhoea case in a heterosexual woman in France, June 2022. The woman was successfully treated with azithromycin 2 g. She had unprotected sex with her regular partner, who developed urethritis following travel to Vietnam and Switzerland. Whole genome sequencing of the gonococcal isolate (F92) identified MLST ST1901, NG-STAR CC- 199, and the novel mosaic penA-237.001, which caused ceftriaxone resistance. penA-237.001 is 98.7% identical to penA-60.001, reported in various ceftriaxone-resistant strains, including the internationally spreading FC428 clone.
引用
收藏
页码：17 / 22
页数：6
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