Regulation of the APC and the exit from mitosis

被引：301
|
作者：
Morgan, DO [1 ]
机构：
[1] Univ Calif San Francisco, Dept Physiol, San Francisco, CA 94143 USA
来源：
NATURE CELL BIOLOGY | 1999年 / 1卷 / 02期
关键词：
D O I：
10.1038/10039
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The events of late mitosis, from sister-chromatid separation to cytokinesis, are governed by the anaphase-promoting complex (APC), a multisubunit assembly that triggers the ubiquitin-dependent proteloysis of key regulatory proteins. An intricate regulatory network governs Ape activity and helps to ensure that late mitotic events are properly timed and coordinated.
引用
收藏
页码：E47 / E53
页数：7
相关论文
共 50 条
  • [1] Regulation of the APC and the exit from mitosis
    David O. Morgan
    Nature Cell Biology, 1999, 1 : E47 - E53
  • [2] Regulation of exit from mitosis in yeast
    Amon, AB
    Bardin, A
    Visintin, R
    FASEB JOURNAL, 2001, 15 (04): : A503 - A503
  • [3] Regulation of APC/C Activators in Mitosis and Meiosis
    Pesin, Jillian A.
    Orr-Weaver, Terry L.
    ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, 2008, 24 : 475 - 499
  • [4] Rewiring the exit from mitosis
    Ciliberto, A
    Lukács, A
    Tóth, A
    Tyson, JJ
    Novák, B
    CELL CYCLE, 2005, 4 (08) : 1107 - 1112
  • [5] Mitosis: entry, exit and emergency exit
    Bornens, M
    M S-MEDECINE SCIENCES, 2003, 19 (03): : 259 - 261
  • [6] Testing cyclin specificity in the exit from mitosis
    Jacobson, MD
    Gray, S
    Yuste-Rojas, M
    Cross, FR
    MOLECULAR AND CELLULAR BIOLOGY, 2000, 20 (13) : 4483 - 4493
  • [7] Exit from mitosis: Spindle pole power
    Hoyt, MA
    CELL, 2000, 102 (03) : 267 - 270
  • [8] Regulation of exit from mitosis in multinucleate Ashbya gossypii cells relies on a minimal network of genes
    Finlayson, Mark R.
    Helfer-Hungerbuehler, A. Katrin
    Philippsen, Peter
    MOLECULAR BIOLOGY OF THE CELL, 2011, 22 (17) : 3081 - 3093
  • [9] Activating the genome during development and exit from mitosis
    Ken Zaret
    Katherine Palozola
    Jan Manuel Caravaca
    Epigenetics & Chromatin, 6 (Suppl 1)
  • [10] A mechanism for coupling exit from mitosis to partitioning of the nucleus
    Bardin, AJ
    Visintin, R
    Amon, A
    CELL, 2000, 102 (01) : 21 - 31
12345