Label-free low-cost disposable DNA hybridization detection systems using organic TFTs

被引:2
|
作者
Zhang, Qintao [1 ]
Subramanian, Vivek [1 ]
机构
[1] Univ Calif Berkeley, Dept Elect Engn & Comp Sci, Berkeley, CA 94720 USA
关键词
D O I
10.1109/IEDM.2007.4418909
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
We report an OTFT-based label-free DNA hybridization detection system integrating electrically-read DNA hybridization sensors and microfluidic delivery channels. We use DNA-doped OTFTs as electrically-read DNA sensors. By integrating with polymer microfluidics, for the first time, we demonstrate the technologies required to realize disposable, rapid turn-around tools for field-deployable genetic diagnosis.
引用
收藏
页码:229 / 232
页数:4
相关论文
共 50 条
  • [41] E-DNA sensors for convenient, label-free electrochemical detection of hybridization
    Francesco Ricci
    Kevin W. Plaxco
    Microchimica Acta, 2008, 163 : 149 - 155
  • [42] Understanding properties of electrified interfaces as a prerequisite for label-free DNA hybridization detection
    Gebala, Magdalena
    Schuhmann, Wolfgang
    PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2012, 14 (43) : 14933 - 14942
  • [43] Gel-immobilized molecular beacons for label-free DNA hybridization detection
    Wang, H
    Li, JO
    Liu, QJ
    Liu, HP
    Lu, ZH
    INTERNATIONAL CONFERENCE ON SENSOR TECHNOLOGY (ISTC 2001), PROCEEDINGS, 2001, 4414 : 40 - 42
  • [44] AlGaN/GaN heterostructure field transistor for label-free detection of DNA hybridization
    WEN XueJin
    WANG ShengNian
    WANG YuJi
    LEE Ly James
    LU Wu
    ChineseScienceBulletin, 2013, 58 (21) : 2601 - 2605
  • [45] Magnetic bead-based label-free electrochemical detection of DNA hybridization
    Wang, J
    Kawde, AN
    Erdem, A
    Salazar, M
    ANALYST, 2001, 126 (11) : 2020 - 2024
  • [46] AlGaN/GaN heterostructure field transistor for label-free detection of DNA hybridization
    Wen XueJin
    Wang ShengNian
    Wang YuJi
    Lee, Ly James
    Lu Wu
    CHINESE SCIENCE BULLETIN, 2013, 58 (21): : 2601 - 2605
  • [47] Label-Free Detection of DNA Hybridization Based on MnO2 Nanoparticles
    Liu, Zhi-Min
    Li, Zhe-Jian
    Shen, Guo-Li
    Yu, Ru-Qin
    ANALYTICAL LETTERS, 2009, 42 (18) : 3046 - 3057
  • [48] Label-Free Highly Sensitive Hybrid Plasmonic Biosensor for the Detection of DNA Hybridization
    Hameed, Mohamed Farhat O.
    Saadeldin, Ahmed Samy
    Elkaramany, Essam M. A.
    Obayya, Salah S. A.
    JOURNAL OF LIGHTWAVE TECHNOLOGY, 2017, 35 (22) : 4851 - 4858
  • [49] Ultrasensitive label-free detection and quantitation of DNA hybridization via terahertz spectrometry
    Rahman, Anis
    Stanley, Bruce
    Rahman, Aunik K.
    IMAGING, MANIPULATION, AND ANALYSIS OF BIOMOLECULES, CELLS, AND TISSUES VIII, 2010, 7568
  • [50] Simple and label-free detection of DNA hybridization on a modified graphene nanosheets electrode
    Benvidi, Ali
    Rajabzadeh, Nooshin
    Zahedi, Hossein Molaye
    Mazloum-Ardakani, Mohammad
    Heidari, Mohammad M.
    Hosseinzadeh, Laleh
    TALANTA, 2015, 137 : 80 - 86