We report an OTFT-based label-free DNA hybridization detection system integrating electrically-read DNA hybridization sensors and microfluidic delivery channels. We use DNA-doped OTFTs as electrically-read DNA sensors. By integrating with polymer microfluidics, for the first time, we demonstrate the technologies required to realize disposable, rapid turn-around tools for field-deployable genetic diagnosis.
机构:
Chinese Univ Hong Kong, Dept Mech & Automat Engn, Shatin, Hong Kong, Peoples R China
Chinese Univ Hong Kong, Shenzhen Res Inst, Shenzhen 518057, Peoples R ChinaChinese Univ Hong Kong, Dept Mech & Automat Engn, Shatin, Hong Kong, Peoples R China
Feng, Fu
Chen, Wang
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Chinese Univ Hong Kong, Dept Mech & Automat Engn, Shatin, Hong Kong, Peoples R China
Chinese Univ Hong Kong, Shenzhen Res Inst, Shenzhen 518057, Peoples R ChinaChinese Univ Hong Kong, Dept Mech & Automat Engn, Shatin, Hong Kong, Peoples R China
Chen, Wang
Chen, Dihan
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机构:
Chinese Univ Hong Kong, Dept Mech & Automat Engn, Shatin, Hong Kong, Peoples R China
Chinese Univ Hong Kong, Shenzhen Res Inst, Shenzhen 518057, Peoples R ChinaChinese Univ Hong Kong, Dept Mech & Automat Engn, Shatin, Hong Kong, Peoples R China
Chen, Dihan
Lin, Wei
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Chinese Univ Hong Kong, Dept Mech & Automat Engn, Shatin, Hong Kong, Peoples R China
Chinese Univ Hong Kong, Shenzhen Res Inst, Shenzhen 518057, Peoples R ChinaChinese Univ Hong Kong, Dept Mech & Automat Engn, Shatin, Hong Kong, Peoples R China
Lin, Wei
Chen, Shih-Chi
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Chinese Univ Hong Kong, Dept Mech & Automat Engn, Shatin, Hong Kong, Peoples R China
Chinese Univ Hong Kong, Shenzhen Res Inst, Shenzhen 518057, Peoples R ChinaChinese Univ Hong Kong, Dept Mech & Automat Engn, Shatin, Hong Kong, Peoples R China
机构:
Korea Res Inst Biosci & Biotechnol, BioNanotechnol Res Ctr, Taejon 305600, South Korea
Univ Sci & Technol, Sch Engn, Taejon 305600, South KoreaKorea Res Inst Biosci & Biotechnol, BioNanotechnol Res Ctr, Taejon 305600, South Korea
Kim, Sang Kyu
Cho, Hyunmin
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机构:
Korea Res Inst Biosci & Biotechnol, BioNanotechnol Res Ctr, Taejon 305600, South Korea
Univ Sci & Technol, Sch Engn, Taejon 305600, South KoreaKorea Res Inst Biosci & Biotechnol, BioNanotechnol Res Ctr, Taejon 305600, South Korea
Cho, Hyunmin
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机构:
Jeong, Jinyoung
Kwon, Ji Na
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机构:
Korea Res Inst Biosci & Biotechnol, BioNanotechnol Res Ctr, Taejon 305600, South Korea
Univ Sci & Technol, Sch Engn, Taejon 305600, South KoreaKorea Res Inst Biosci & Biotechnol, BioNanotechnol Res Ctr, Taejon 305600, South Korea
Kwon, Ji Na
Jung, Yongwon
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Korea Res Inst Biosci & Biotechnol, BioNanotechnol Res Ctr, Taejon 305600, South Korea
Univ Sci & Technol, Sch Engn, Taejon 305600, South KoreaKorea Res Inst Biosci & Biotechnol, BioNanotechnol Res Ctr, Taejon 305600, South Korea
Jung, Yongwon
Chung, Bong Hyun
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Korea Res Inst Biosci & Biotechnol, BioNanotechnol Res Ctr, Taejon 305600, South Korea
Univ Sci & Technol, Sch Engn, Taejon 305600, South KoreaKorea Res Inst Biosci & Biotechnol, BioNanotechnol Res Ctr, Taejon 305600, South Korea
机构:
Univ Roma Tor Vergata, Dipartimento Sci & Tecnol Chim, I-00133 Rome, ItalyUniv Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA
Ricci, Francesco
Plaxco, Kevin W.
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机构:
Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA
Univ Calif Santa Barbara, Biomol Sci & Engn Program, Santa Barbara, CA 93106 USAUniv Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA