Facile Synthesis of 4-Substituted-2-quinolinone-3-carboxylic Acid Ethyl Esters

被引：0
|
作者：
Zhang, Lijuan [1 ]
Luo, Yu [1 ]
Yu, Shanbao [1 ]
Lu, Wei [1 ,2 ]
机构：
[1] E China Normal Univ, Dept Chem, Shanghai 200062, Peoples R China
[2] E China Normal Univ, Inst Drug Discovery & Dev, iAIR, Shanghai 200062, Peoples R China
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2012年 / 49卷 / 05期
关键词：
KINASE INHIBITORS; ACTIVATION; DESIGN;
D O I：
10.1002/jhet.967
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient route for the synthesis of 4-substituted-2-quinolinone-3-carboxylic acid ethyl esters has been developed through Suzuki or Sonogashira reactions. The advantages of the method include high yields, operational simplicity, and suitability for medicinal modification of 4-substituted quinolinones and their derivatives.
引用
收藏
页码：1254 / 1256
页数：3
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