Hepatitis C Viral Kinetics The Past, Present, and Future

被引：21
|
作者：
Chatterjee, Anushree [1 ,2 ]
Smith, Patrick F. [3 ]
Perelson, Alan S. [1 ]
机构：
[1] Los Alamos Natl Lab, Theoret Biol & Biophys, Los Alamos, NM 87545 USA
[2] Los Alamos Natl Lab, Ctr Nonlinear Studies, Los Alamos, NM 87545 USA
[3] Roche, Clin Pharmacol Pharma Res & Early Dev, Nutley, NJ USA
来源：
CLINICS IN LIVER DISEASE | 2013年 / 17卷 / 01期
关键词：
Mathematical modeling; Viral kinetics; Direct-acting antiviral agents; Protease inhibitors; Hepatitis C virus; DYNAMICS IN-VIVO; POLYMERASE INHIBITOR; ANTIVIRAL ACTIVITY; PROTEASE INHIBITORS; VIRUS-REPLICATION; TREATMENT-NAIVE; NONNUCLEOSIDE POLYMERASE; RESISTANCE MUTATIONS; ALPHA-INTERFERON; WILD-TYPE;
D O I：
10.1016/j.cld.2012.09.003
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Mathematical modeling of hepatitis C viral kinetics has been an important tool in understanding hepatitis C virus (HCV) infection dynamics and in estimating crucial in vivo parameters characterizing the effectiveness of HCV therapy. Because of the introduction of direct-acting antiviral agents, there is a need to extend previous models so as to understand, characterize, and compare various new HCV treatment regimens. Here we review recent modeling efforts in this direction.
引用
收藏
页码：13 / +
页数：15
相关论文
共 50 条
  • [31] Viral hepatitis associated hepatocellular carcinoma on the African continent, the past, present, and future: a systematic review
    Dakurah, Ottovon Bismark
    Tamandjou, Cynthia Raissa Tchuem
    Zunza, Moleen
    Preiser, Wolfgang
    Maponga, Tongai Gibson
    BMC CANCER, 2021, 21 (01)
  • [32] Paediatric hepatitis C virus infection and its treatment: Present, past, and future
    El-Shabrawi, Mortada
    Hassanin, Fetouh
    ARAB JOURNAL OF GASTROENTEROLOGY, 2019, 20 (03) : 163 - 174
  • [33] C&C Past, Present and Future
    Edmonds, Ernest
    C&C'21: PROCEEDINGS OF THE 13TH CONFERENCE ON CREATIVITY AND COGNITION, 2021,
  • [34] Viral vectors for gene therapy: Past, present and future
    Strayer, DS
    DRUG NEWS & PERSPECTIVES, 1998, 11 (05) : 277 - 286
  • [35] VIRAL EVOLUTION Past, present and future of influenza viruses
    Hofer, Ursula
    NATURE REVIEWS MICROBIOLOGY, 2014, 12 (04) : 237 - 237
  • [36] SENSE AND NONSENSE IN VIRAL DIAGNOSIS - PAST, PRESENT, AND FUTURE
    MCINTOSH, K
    CURRENT TOPICS IN MICROBIOLOGY AND IMMUNOLOGY, 1983, 104 : 1 - 6
  • [37] Viral vaccines for bony fish: past, present and future
    Salgado-Miranda, Celene
    Loza-Rubio, Elizabeth
    Rojas-Anaya, Edith
    Garcia-Espinosa, Gary
    EXPERT REVIEW OF VACCINES, 2013, 12 (05) : 567 - 578
  • [38] Viral detection by electron microscopy: past, present and future
    Roingeard, Philippe
    BIOLOGY OF THE CELL, 2008, 100 (08) : 491 - 501
  • [39] C — Past, present, and future — A perspective
    K. Bhaskar
    Resonance, 2012, 17 (8) : 748 - 758
  • [40] C - Past, Present, and Future - A Perspective
    Bhaskar, K.
    RESONANCE-JOURNAL OF SCIENCE EDUCATION, 2012, 17 (08): : 748 - 758
12345