An MRI study of amygdala in schizophrenia and psychotic bipolar disorder

被引：20

作者：

Mahon, Pamela Belmonte ^{[1
]}

Eldridge, Haley ^{[1
]}

Crocker, Britni ^{[2
]}

Notes, Lisa ^{[1
]}

Gindes, Holly ^{[1
]}

Postell, Elizabeth ^{[2
]}

King, Stacey ^{[1
]}

Potash, James B. ^{[1
]}

Ratnanather, J. Tilak ^{[2
,3
]}

Barta, Patrick E. ^{[2
]}

机构：

[1] Johns Hopkins Sch Med, Dept Psychiat & Behav Sci, Baltimore, MD USA

[2] Johns Hopkins Univ, Ctr Imaging Sci, Baltimore, MD USA

[3] Johns Hopkins Univ, Inst Computat Med, Baltimore, MD USA

来源：

SCHIZOPHRENIA RESEARCH | 2012年 / 138卷 / 2-3期

关键词：

Amygdala; MRI; Psychotic bipolar disorder; Schizophrenia; ADULT HUMAN BRAIN; HIPPOCAMPAL-FORMATION; ALZHEIMERS-DISEASE; VOLUMES; METAANALYSIS; SEX; CLASSIFICATION; INTERVIEW; FEATURES; LITHIUM;

D O I：

10.1016/j.schres.2012.04.005

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Meta-analyses report larger amygdala in subjects with bipolar disorder compared to schizophrenia. However, few studies have compared the size of amygdala in psychotic bipolar disorder with schizophrenia. Here we examine size of amygdala in a sample of 36 patients with psychotic bipolar disorder, 31 patients with schizophrenia and 27 healthy comparison subjects. Patients with schizophrenia had smaller amygdala compared with patients with psychotic bipolar disorder (p=0.014). These results suggest that change in volume of amygdala may represent a morphologic feature distinguishing psychotic bipolar disorder from schizophrenia. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：188 / 191

页数：4

共 50 条

[41] Dopamine transporter abnormalities in the amygdala of subjects diagnosed with schizophrenia or bipolar disorder
Berretta, S.
Sin, J. M.
Pantazopoulos, H.
Liu, Y.
SCHIZOPHRENIA BULLETIN, 2007, 33 (02) : 269 - 269
[42] Quality of life of people with schizophrenia, bipolar disorder and other psychotic disorders
Saarni, Samuli I.
Viertio, Satu
Perala, Jonna
Koskinen, Seppo
Lonnqvist, Jouko
Suvisaari, Jaana
BRITISH JOURNAL OF PSYCHIATRY, 2010, 197 (05) : 386 - 394
[43] Neuropsychological functioning in early and chronic stages of schizophrenia and psychotic bipolar disorder
Menkes, Margo W.
Armstrong, Kristan
Blackford, Jennifer Urbano
Heckers, Stephan
Woodward, Neil D.
SCHIZOPHRENIA RESEARCH, 2019, 206 : 413 - 419
[44] The intiating step of the kynurenine pathway is upregulated in schizophrenia psychotic bipolar disorder
Miller, CL
Llenos, IC
Dulay, JR
Yolken, RH
Weis, S
SCHIZOPHRENIA BULLETIN, 2005, 31 (02) : 253 - 253
[45] Prefrontal gyrification in psychotic bipolar I disorder vs. schizophrenia
Nenadic, Igor
Maitra, Raka
Dietzek, Maren
Langbein, Kerstin
Smesny, Stefan
Sauer, Heinrich
Gaser, Christian
JOURNAL OF AFFECTIVE DISORDERS, 2015, 185 : 104 - 107
[46] NEUROPSYCHOLOGICAL FUNCTIONING IN EARLY AND CHRONIC STAGES OF SCHIZOPHRENIA AND PSYCHOTIC BIPOLAR DISORDER
Menkes, Margo
Armstrong, Kristan
Blackford, Jennifer
Heckers, Stephan
Woodward, Neil
SCHIZOPHRENIA BULLETIN, 2019, 45 : S273 - S274
[47] Insight and neuropsychological function in patients with schizophrenia and bipolar disorder with psychotic features
Arduini, L
Kalyvoka, A
Stratta, P
Rinaldi, O
Daneluzzo, E
Rossi, A
CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE, 2003, 48 (05): : 338 - 341
[48] Cerebellar volume in schizophrenia and bipolar I disorder with and without psychotic features
Laidi, C.
d'Albis, M. -A.
Wessa, M.
Linke, J.
Phillips, M. L.
Delavest, M.
Bellivier, F.
Versace, A.
Almeida, J.
Sarrazin, S.
Poupon, C.
Le Dudal, K.
Daban, C.
Hamdani, N.
Leboyer, M.
Houenou, J.
ACTA PSYCHIATRICA SCANDINAVICA, 2015, 131 (03) : 223 - 233
[49] BRAIN STRUCTURE IN NEUROPSYCHOLOGICALLY DEFINED SUBGROUPS OF SCHIZOPHRENIA AND PSYCHOTIC BIPOLAR DISORDER
Woodward, Neil
Heckers, S.
SCHIZOPHRENIA BULLETIN, 2015, 41 : S281 - S282
[50] Evoked Response Potential Endophenotypes Link Schizophrenia and Psychotic Bipolar Disorder
Hurwitz, Nathaniel G.
Aires, Daniel J.
PSYCHIATRIC ANNALS, 2010, 40 (03) : 149 - 153

← 1 2 3 4 5 →