An MRI study of amygdala in schizophrenia and psychotic bipolar disorder

被引：20
|
作者：
Mahon, Pamela Belmonte [1 ]
Eldridge, Haley [1 ]
Crocker, Britni [2 ]
Notes, Lisa [1 ]
Gindes, Holly [1 ]
Postell, Elizabeth [2 ]
King, Stacey [1 ]
Potash, James B. [1 ]
Ratnanather, J. Tilak [2 ,3 ]
Barta, Patrick E. [2 ]
机构：
[1] Johns Hopkins Sch Med, Dept Psychiat & Behav Sci, Baltimore, MD USA
[2] Johns Hopkins Univ, Ctr Imaging Sci, Baltimore, MD USA
[3] Johns Hopkins Univ, Inst Computat Med, Baltimore, MD USA
来源：
SCHIZOPHRENIA RESEARCH | 2012年 / 138卷 / 2-3期
关键词：
Amygdala; MRI; Psychotic bipolar disorder; Schizophrenia; ADULT HUMAN BRAIN; HIPPOCAMPAL-FORMATION; ALZHEIMERS-DISEASE; VOLUMES; METAANALYSIS; SEX; CLASSIFICATION; INTERVIEW; FEATURES; LITHIUM;
D O I：
10.1016/j.schres.2012.04.005
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Meta-analyses report larger amygdala in subjects with bipolar disorder compared to schizophrenia. However, few studies have compared the size of amygdala in psychotic bipolar disorder with schizophrenia. Here we examine size of amygdala in a sample of 36 patients with psychotic bipolar disorder, 31 patients with schizophrenia and 27 healthy comparison subjects. Patients with schizophrenia had smaller amygdala compared with patients with psychotic bipolar disorder (p=0.014). These results suggest that change in volume of amygdala may represent a morphologic feature distinguishing psychotic bipolar disorder from schizophrenia. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码：188 / 191
页数：4
相关论文
共 50 条
  • [31] Neurocognition in patients with psychotic and non-psychotic bipolar I disorder. A comparative study with individuals with schizophrenia
    Jimenez-Lopez, Estela
    Isabel Aparicio, Ana
    Maria Sanchez-Morla, Eva
    Rodriguez-Jimenez, Roberto
    Vieta, Eduard
    Luis Santos, Jose
    JOURNAL OF AFFECTIVE DISORDERS, 2017, 222 : 169 - 176
  • [32] Subcortical Volume Changes in Schizophrenia and Bipolar Disorder: A Quantitative MRI Study
    Demir, Mehmet
    Findikli, Ebru
    Tuncel, Deniz
    Atay, Emre
    Baykara, Murat
    Acer, Niyazi
    Doganer, Adem
    INTERNATIONAL JOURNAL OF MORPHOLOGY, 2024, 42 (02): : 503 - 509
  • [33] Brain structure in schizophrenia vs. psychotic bipolar I disorder: A VBM study
    Nenadic, Igor
    Maitra, Raka
    Langbein, Kerstin
    Dietzek, Maren
    Lorenz, Carsten
    Smesny, Stefan
    Reichenbach, Juergen R.
    Sauer, Heinrich
    Gaser, Christian
    SCHIZOPHRENIA RESEARCH, 2015, 165 (2-3) : 212 - 219
  • [34] Parietal lobe and disorganisation syndrome in schizophrenia and psychotic bipolar disorder: A bimodal connectivity study
    Das, Tushar K.
    Kumar, Jyothika
    Francis, Susan
    Liddle, Peter F.
    Palaniyappan, Lena
    PSYCHIATRY RESEARCH-NEUROIMAGING, 2020, 303
  • [35] Predictors of Remission, Schizophrenia, and Bipolar Disorder in Adolescents with Brief Psychotic Disorder or Psychotic Disorder Not Otherwise Specified Considered At Very High Risk for Schizophrenia
    Correll, Christoph U.
    Smith, Christopher W.
    Auther, Andrea M.
    McLaughlin, Danielle
    Shah, Manoj
    Foley, Carmel
    Olsen, Ruth
    Lencz, Todd
    Kane, John M.
    Cornblatt, Barbara A.
    JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, 2008, 18 (05) : 475 - 490
  • [36] Electroencephalographic delta/alpha frequency activity differentiates psychotic disorders: a study of schizophrenia, bipolar disorder and methamphetamine-induced psychotic disorder
    Fleur M Howells
    Hendrik S Temmingh
    Jennifer H Hsieh
    Andrea V van Dijen
    David S Baldwin
    Dan J Stein
    Translational Psychiatry, 8
  • [37] Electroencephalographic delta/alpha frequency activity differentiates psychotic disorders: a study of schizophrenia, bipolar disorder and methamphetamine-induced psychotic disorder
    Howells, Fleur M.
    Temmingh, Hendrik S.
    Hsieh, Jennifer H.
    van Dijen, Andrea V.
    Baldwin, David S.
    Stein, Dan J.
    TRANSLATIONAL PSYCHIATRY, 2018, 8
  • [38] WORKING MEMORY AND BRAIN ACTIVATION IN SCHIZOPHRENIA VS. PSYCHOTIC BIPOLAR I DISORDER ASSESSED WITH FUNCTIONAL MRI
    Nenadic, Igor
    Langbein, Kerstin
    Dietzek, Maren
    Maitra, Raka
    Mingoia, Gianluca
    Smesny, Stefan
    Wagner, Gerd
    Schloesser, Ralf
    Gaser, Christian
    Sauer, Heinrich
    SCHIZOPHRENIA RESEARCH, 2014, 153 : S202 - S202
  • [39] Psychosocial functioning in patients with psychotic and non-psychotic bipolar I disorder. A comparative study with individuals with schizophrenia
    Jimenez-Lopez, Estela
    Maria Sanchez-Morla, Eva
    Isabel Aparicio, Ana
    Lopez-Villarreal, Ana
    Martinez-Vizcaino, Vicente
    Rodriguez-Jimenez, Roberto
    Vieta, Eduard
    Luis Santos, Jose
    JOURNAL OF AFFECTIVE DISORDERS, 2018, 229 : 177 - 185
  • [40] EFFECT OF EARLY CANNABIS USE ON COGNITION IN SCHIZOPHRENIA AND PSYCHOTIC BIPOLAR DISORDER
    Dodig, Darko
    Cole, D.
    Moates, Amanda F.
    Witte, B.
    Ivleva, Elena I.
    Cullum, M.
    Tamminga, C.
    Ghose, Subroto
    SCHIZOPHRENIA BULLETIN, 2011, 37 : 205 - 205
12345