Stereoselective synthesis of the C79-C97 fragment of symbiodinolide

被引：4
|
作者：
Takamura, Hiroyoshi [1 ]
Fujiwara, Takayuki [1 ]
Kadota, Isao [1 ]
Uemura, Daisuke [2 ]
机构：
[1] Okayama Univ, Dept Chem, Grad Sch Nat Sci & Technol, Kita Ku, Okayama 7008530, Japan
[2] Kanagawa Univ, Dept Chem, Fac Sci, Hiratsuka, Kanagawa 2591293, Japan
来源：
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 9卷
基金：
日本学术振兴会;
关键词：
Julia-Kocienski olefination; polyol marine natural product; Sharpless asymmetric dihydroxylation; spiroacetalization; symbiodinolide; ABSOLUTE-CONFIGURATION; STEREOCONTROLLED SYNTHESIS; C33-C42; FRAGMENT; CONDENSATION; OXIDATION; ALDEHYDES;
D O I：
10.3762/bjoc.9.228
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Symbiodinolide is a polyol marine natural product with a molecular weight of 2860. Herein, a streamlined synthesis of the C79-C97 fragment of symbiodinolide is described. In the synthetic route, a spiroacetalization, a Julia-Kocienski olefination, and a Sharpless asymmetric dihydroxylation were utilized as the key transformations.
引用
收藏
页码：1931 / 1935
页数：5
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