QUANTITATIVE SYSTEMS PHARMACOLOGY MODELING OF T CELL ACTIVATION AND CD28/CTLA4 CO-SIGNALING INTERACTION.

被引:0
|
作者
Holland, D. [1 ]
Ji, Y. [2 ]
Gomes, B. [3 ]
机构
[1] Johns Hopkins Sch Med, Baltimore, MD USA
[2] Novartis, E Hanover, NJ USA
[3] Novartis, Cambridge, MA USA
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
PI-093
引用
收藏
页码:S39 / S39
页数:1
相关论文
共 50 条
  • [21] CD28/CTLA-4 RECEPTOR STRUCTURE, BINDING STOICHIOMETRY AND AGGREGATION DURING T-CELL ACTIVATION
    LINSLEY, PS
    LEDBETTER, J
    PEACH, R
    BAJORATH, J
    RESEARCH IN IMMUNOLOGY, 1995, 146 (03): : 130 - 140
  • [22] Expression of CD28 and CTLA4 on T cells in bone morrow of immune-mediated aplastic anemia mice
    Liu Zhenfang
    Sun Hanying
    Liu Wenli
    Luo Xiaohua
    He Li
    Xu Huizhen
    Journal of Huazhong University of Science and Technology [Medical Sciences], 2005, 25 (5): : 508 - 509
  • [23] Expression of CD28 and CTLA4 on T Cells in Bone Morrow of Immune-mediated Aplastic Anemia Mice
    刘振芳
    孙汉英
    刘文励
    罗小华
    何莉
    徐慧珍
    华中科技大学学报(医学英德文版), 2005, (05) : 508 - 509
  • [24] Positive and negative regulation of human T cell activation mediated by the CTLA-4/CD28 ligand CD80
    Boulougouris, G
    McLeod, JD
    Patel, YI
    Ellwood, CN
    Walker, LSK
    Sansom, DM
    JOURNAL OF IMMUNOLOGY, 1998, 161 (08): : 3919 - 3924
  • [25] Regulation of human T cell activation and death through agonistic CD28 signaling
    Slusser, JG
    Rodgers, JR
    Lewis, DE
    CYTOMETRY PART A, 2004, 59A (01): : 55 - 55
  • [26] CD28 and CTLA-4 control T cell activation through regulation of cbl-b expression.
    Li, DD
    Vermes, C
    Gál, I
    Finnegan, AG
    Mikecz, K
    Glant, TT
    Jian, Z
    ARTHRITIS AND RHEUMATISM, 2002, 46 (09): : S487 - S487
  • [27] Co-stimulatory receptors CD28 and CTLA4 are required for optimal NK cell effector function and memory formation during MCMV infection
    Karo, Jenny
    Sun, Joseph
    JOURNAL OF IMMUNOLOGY, 2012, 188
  • [28] The landscape of CD28, CD80, CD86, CTLA4, and ICOS DNA methylation in head and neck squamous cell carcinomas
    de Vos, Luka
    Gruenwald, Ingela
    Bawden, Emma Grace
    Dietrich, Joern
    Scheckenbach, Kathrin
    Wiek, Constanze
    Zarbl, Romina
    Bootz, Friedrich
    Landsberg, Jennifer
    Dietrich, Dimo
    EPIGENETICS, 2020, 15 (11) : 1195 - 1212
  • [29] CD28 co-receptor signal transduction in T-cell activation
    Blair, PJ
    Riley, JL
    Carroll, RG
    StLouis, DC
    Levine, BL
    Saha, B
    Lee, KP
    Perrin, PJ
    Harlan, DM
    June, CH
    BIOCHEMICAL SOCIETY TRANSACTIONS, 1997, 25 (02) : 651 - 657
  • [30] Predictive and prognostic significance of T cell surface CD28 and CTLA-4 levels in hemophilia
    Li, Lingling
    Li, Xiumin
    Liu, Kai
    Xue, Jie
    Wang, Dongni
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2020, 13 (09): : 6297 - 6305