Medicated Intraocular Lenses

被引：0
|
作者：
Eperon, S. [1 ]
Bossy-Nobs, L.
Petropoulos, I. K. [1 ]
Gurny, R.
Guex-Crosier, Y. [1 ]
机构：
[1] Univ Lausanne, Jules Gonin Eye Hosp, CH-1000 Lausanne 7, Switzerland
来源：
PROCEEDINGS OF THE 7TH INTERNATIONAL SYMPOSIUM ON OCULAR PHARMACOLOGY AND THERAPEUTICS | 2008年
关键词：
D O I：
暂无
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
In order to decrease postoperative inflammation after cataract surgery, we developed a biodegradable drug delivery system (DDS) combined with the artificial intraocular lens (IOL). DDS were prepared using poly(lactide-co-glycolide) or PLGA of various molecular weight and were loaded with triamcinolone acetonide (TA). In vitro, the higher the Mw of PLGA, the slower was the cumulative release of TA. Cataract Surgery was performed in rabbits and DDS combined with IOL was inserted. Our DDS were shown to inhibit inflammation caused by cataract surgery.
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页码：21 / +
页数：3
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