How Tumor Virology Evolved into Cancer Biology and Transformed Oncology

被引：10
|
作者：
Varmus, Harold [1 ]
机构：
[1] Weill Cornell Med, Meyer Canc Ctr, New York, NY 10065 USA
来源：
ANNUAL REVIEW OF CANCER BIOLOGY, VOL 1 | 2017年 / 1卷
关键词：
retroviruses; oncogenes; genomics; targeted therapy; oncology; DEPENDENT DNA-POLYMERASE; AVIAN-SARCOMA VIRUSES; GENE; INHIBITOR; SEQUENCES; ONCOGENE; IDENTIFICATION; SUPPRESSION; ACTIVATION; HALLMARKS;
D O I：
10.1146/annurev-cancerbio-050216-034315
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The field of cancer biology has recently come of age, as witnessed by the initiation of this Annual Reviews journal this year. In this article, I argue that the major sources of cancer biology reside neither in cell biology nor in traditional cancer research, but instead in the domain once called "tumor virology." Speaking from the perspective of someone who "rode the wave" that uncovered cancer genes and their effects on cell behavior, I have tried to trace the influences, discoveries, and changing attitudes and practices that produced the vibrant scientific landscape that we now enjoy.
引用
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页码：1 / 18
页数：18
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