Size matters in nanoscale communication

被引：111

作者：

Zijlstra, Andries ^{[1
,2
]}

Di Vizio, Dolores ^{[3
,4
,5
]}

机构：

[1] Vanderbilt Univ, Med Ctr, Dept Pathol Microbiol & Immunol, Nashville, TN USA

[2] Vanderbilt Univ, Med Ctr, Program Canc Biol, Nashville, TN USA

[3] Cedars Sinai Med Ctr, Dept Surg, Los Angeles, CA 90048 USA

[4] Cedars Sinai Med Ctr, Dept Biomed Sci, Los Angeles, CA 90048 USA

[5] Cedars Sinai Med Ctr, Dept Pathol & Lab Med, Los Angeles, CA 90048 USA

来源：

NATURE CELL BIOLOGY | 2018年 / 20卷 / 03期

关键词：

EXTRACELLULAR VESICLES; EXOSOMES; CANCER; MICROVESICLES;

D O I：

10.1038/s41556-018-0049-8

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Exosomes are heterogeneous, nanoscale vesicles that mediate cellular communication. A study now leverages a size separation strategy to identify sub-classes of nanoparticles, revealing a subtype without an encapsulating membrane and variation in vesicle cargo, suggesting that size is not the only driver of heterogeneity.

引用

页码：228 / 230

页数：4

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