Size matters in nanoscale communication

被引:111
|
作者
Zijlstra, Andries [1 ,2 ]
Di Vizio, Dolores [3 ,4 ,5 ]
机构
[1] Vanderbilt Univ, Med Ctr, Dept Pathol Microbiol & Immunol, Nashville, TN USA
[2] Vanderbilt Univ, Med Ctr, Program Canc Biol, Nashville, TN USA
[3] Cedars Sinai Med Ctr, Dept Surg, Los Angeles, CA 90048 USA
[4] Cedars Sinai Med Ctr, Dept Biomed Sci, Los Angeles, CA 90048 USA
[5] Cedars Sinai Med Ctr, Dept Pathol & Lab Med, Los Angeles, CA 90048 USA
关键词
EXTRACELLULAR VESICLES; EXOSOMES; CANCER; MICROVESICLES;
D O I
10.1038/s41556-018-0049-8
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Exosomes are heterogeneous, nanoscale vesicles that mediate cellular communication. A study now leverages a size separation strategy to identify sub-classes of nanoparticles, revealing a subtype without an encapsulating membrane and variation in vesicle cargo, suggesting that size is not the only driver of heterogeneity.
引用
收藏
页码:228 / 230
页数:4
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