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Size matters in nanoscale communication
被引:111
|作者:
Zijlstra, Andries
[1
,2
]
Di Vizio, Dolores
[3
,4
,5
]
机构:
[1] Vanderbilt Univ, Med Ctr, Dept Pathol Microbiol & Immunol, Nashville, TN USA
[2] Vanderbilt Univ, Med Ctr, Program Canc Biol, Nashville, TN USA
[3] Cedars Sinai Med Ctr, Dept Surg, Los Angeles, CA 90048 USA
[4] Cedars Sinai Med Ctr, Dept Biomed Sci, Los Angeles, CA 90048 USA
[5] Cedars Sinai Med Ctr, Dept Pathol & Lab Med, Los Angeles, CA 90048 USA
关键词:
EXTRACELLULAR VESICLES;
EXOSOMES;
CANCER;
MICROVESICLES;
D O I:
10.1038/s41556-018-0049-8
中图分类号:
Q2 [细胞生物学];
学科分类号:
071009 ;
090102 ;
摘要:
Exosomes are heterogeneous, nanoscale vesicles that mediate cellular communication. A study now leverages a size separation strategy to identify sub-classes of nanoparticles, revealing a subtype without an encapsulating membrane and variation in vesicle cargo, suggesting that size is not the only driver of heterogeneity.
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页码:228 / 230
页数:4
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