Spectrally encoded photoacoustic microscopy using a digital mirror device

被引：16

作者：

Wang, Yu ^{[1
]}

Maslov, Konstantin ^{[1
]}

Wang, Lihong V. ^{[1
]}

机构：

[1] Washington Univ, Opt Imaging Lab, Dept Biomed Engn, St Louis, MO 63130 USA

来源：

JOURNAL OF BIOMEDICAL OPTICS | 2012年 / 17卷 / 06期

基金：

美国国家卫生研究院;

关键词：

photoacoustic microscopy; spectral encoding; Hadamard encoding; digital mirror device; photoacoustic spectroscopy; wavelength multiplexing; MULTISPECTRAL OPTOACOUSTIC TOMOGRAPHY; IN-VIVO; LASER;

D O I：

10.1117/1.JBO.17.6.066020

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We have developed spectrally encoded photoacoustic microscopy using a digital mirror device for multi-wavelength tomography, which enables fast spectral imaging of optical absorption. The optical illumination wavelengths are multiplexed at a laser pulse repetition rate of similar to 2 kHz. Liquid samples, whole blood, and blood vessels in mouse ears were imaged. Compared with internal wavelength tuning of a narrow-band laser, external wavelength tuning based on a digital mirror device improves the data acquisition speed of spectral photoacoustic microscopy. Compared with external wavelength scanning of a wide-band laser with the same pulse energy, spectral encoding improves the signal-to-noise ratio. (C) 2012 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.JBO.17.6.066020]

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页数：5

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