Smartphone based Pentraxin 3 enzyme-linked immunosorbent assay for point-of-care cardiovascular disease monitoring

被引：0
|
作者：
Li, Wei [1 ]
Dai, Bo [1 ]
Chen, Shujing [1 ]
Zheng, Lulu [1 ]
Wang, Xuhua [1 ]
Zhang, Dawei [1 ]
机构：
[1] Univ Shanghai Sci & Technol, Minist Educ, Engn Res Ctr Opt Instrument & Syst, Shanghai Key Lab Modern Opt Syst, Shanghai, Peoples R China
来源：
2018 ASIA COMMUNICATIONS AND PHOTONICS CONFERENCE (ACP) | 2018年
基金：
中国国家自然科学基金;
关键词：
Cardiovascular disease; point-of-care testing; Pentraxin; 3; colorimetric algorithm; LONG PENTRAXIN; PTX3;
D O I：
暂无
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
A smartphone based remote colorimetric bioanalytical assay for cardiovascular disease monitoring is proposed and demonstration. The end user only needs to take a photo of Pentraxin 3 reaction product and upload the image to the server by using a customized iOS app and a home-made portable microplate gadget. The image processing, concentration calculation and data recoding are done on the server side. The end user can receive the report immediately. Clinical testing for 40 CVD patient samples is conducted. The testing results obtained by the proposed method agree well with those measured by the commercial plate reader. The compact microplate gadget, user-friendly app, reliable colorimetric analytical algorithm and wireless connection approach make the proposed method a good candidate for point-of-care applications.
引用
收藏
页数：3
相关论文
共 50 条
  • [41] Monoclonal-based enzyme-linked immunosorbent assay and immunochromatographic rapid assay for monensin
    Watanabe, H
    Satake, A
    Matsumoto, M
    Kido, Y
    Tsuji, A
    Ito, K
    Maeda, M
    ANALYST, 1998, 123 (12) : 2573 - 2578
  • [42] Bionanocapsule-based enzyme-antibody conjugates for enzyme-linked immunosorbent assay
    Iijima, Masumi
    Matsuzaki, Takashi
    Kadoya, Hiroyasu
    Hatahira, Satoko
    Hiramatsu, Shingo
    Jung, Giman
    Tanizawa, Katsuyuki
    Kuroda, Shun'ichi
    ANALYTICAL BIOCHEMISTRY, 2010, 396 (02) : 257 - 261
  • [43] A rapid, quantitative enzyme-linked immunosorbent assay (ELISA) for the immunodiagnosis of Chagas' disease
    Partel, CD
    Rossi, CL
    IMMUNOLOGICAL INVESTIGATIONS, 1998, 27 (1-2) : 89 - 96
  • [44] Development of a novel enzyme-linked immunosorbent assay for the diagnosis of Johne's disease
    Eda, S.
    Branscum, A. J.
    Kaneko, Y.
    Scott, M. C.
    Speer, C. A.
    JOURNAL OF DAIRY SCIENCE, 2007, 90 : 7 - 8
  • [45] ENZYME-LINKED IMMUNOSORBENT-ASSAY (ELISA) IN THE SERODIAGNOSIS OF HYDATID-DISEASE
    IACONA, A
    PINI, C
    VICARI, G
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1980, 29 (01): : 95 - 102
  • [46] AN ENZYME-LINKED IMMUNOSORBENT-ASSAY (ELISA) FOR INFECTIOUS BURSAL DISEASE VIRUS
    HOWIE, R
    THORSEN, J
    CANADIAN JOURNAL OF COMPARATIVE MEDICINE-REVUE CANADIENNE DE MEDECINE COMPAREE, 1981, 45 (01): : 51 - 55
  • [47] Tissue transglutaminase autoantibody enzyme-linked immunosorbent assay in detecting celiac disease
    Sulkanen, S
    Halttunen, T
    Laurila, A
    Kolho, KL
    Korponay-Szabó, IR
    Sarnesto, A
    Savilahti, E
    Collin, P
    Mäki, M
    GASTROENTEROLOGY, 1998, 115 (06) : 1322 - 1328
  • [48] The correlation of indirect immunofluorescence, enzyme-linked immunosorbent assay and disease activity in pemphigus
    Reynaert, S
    Bhogal, B
    Oyama, Y
    Powell, AM
    Albert, S
    Harman, K
    Black, MM
    BRITISH JOURNAL OF DERMATOLOGY, 2004, 151 : 5 - 6
  • [49] Development of a novel enzyme-linked immunosorbent assay for the diagnosis of Johne's disease
    Branscum, A. J.
    Kaneko, Y.
    Scott, M. C.
    Speer, C. A.
    JOURNAL OF ANIMAL SCIENCE, 2007, 85 : 7 - 8
  • [50] Development of a novel enzyme-linked immunosorbent assay for the diagnosis of Johne's disease
    Eda, S.
    Branscum, A. J.
    Kaneko, Y.
    Scott, M. C.
    Speer, C. A.
    POULTRY SCIENCE, 2007, 86 : 7 - 8
12345