Green synthesis and anti-infective activities of fluorinated pyrazoline derivatives

被引：70
|
作者：
Shelke, Sharad N. [2 ]
Mhaske, Ganesh R. [2 ]
Bonifacio, Vasco D. B. [1 ]
Gawande, Manoj B. [1 ]
机构：
[1] Univ Nova Lisboa, Fac Ciencias & Tecnol, Dept Quim, REQUIMTE, P-2829516 Caparica, Portugal
[2] SSGM Coll, Dept Chem, Kopargaon 423601, MH, India
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2012年 / 22卷 / 17期
关键词：
Green synthesis; Ultrasonic irradiation; MDR-TB; Anti-infective activity; Pyrazolines;
D O I：
10.1016/j.bmcl.2012.06.072
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A new series of fluorinated pyrazoles, 4a-e, were synthesized in good to excellent overall yields (65-82%) from the corresponding chalcones, 3a-e, by ultrasonic irradiation. The newly synthesized compounds were characterized and screened for their in vitro anti-bacterial, anti-fungal, and anti-tubercular activities against Mycobacterium tuberculosis H(37)Rv. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码：5727 / 5730
页数：4
相关论文
共 50 条
  • [21] Evaluation of triazole and isoxazole derivatives as potential anti-infective agents
    Tarawneh, Amer H.
    Al-Momani, Lo'ay A.
    Leon, Francisco
    Jain, Surenda K.
    Gadetskaya, Anastassiya V.
    Abu-Orabi, Sultan T.
    Tekwani, Babu L.
    Cutler, Stephen J.
    MEDICINAL CHEMISTRY RESEARCH, 2018, 27 (04) : 1269 - 1275
  • [22] STUDIES ON QUINOLINE DERIVATIVES AS ANTI-INFECTIVE AGENTS .1.
    BAHAL, SM
    BAICHWAL, MR
    KHORANA, ML
    JOURNAL OF PHARMACEUTICAL SCIENCES, 1961, 50 (02) : 127 - &
  • [23] Synthesis and antinociceptive activities of some pyrazoline derivatives
    Kaplancikli, Zafer Asim
    Turan-Zitouni, Guelhan
    Ozdemir, Ahmet
    Can, Oezguer Devrim
    Chevallet, Pierre
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2009, 44 (06) : 2606 - 2610
  • [24] Exploring green synthesis and characterization of ZIF-8 and recent developments in anti-infective applications
    Suliman, Muath
    Altalbawy, Farag M. A.
    Kaur, Mandeep
    Jain, Vicky
    Ariffin, I. A.
    Kumari, Bharti
    Saini, Suman
    Kubaev, Aziz
    Hussein, Uday Abdul-Reda
    Edan, Reem Turki
    Abdulhussain, Munthir Abdulwahid
    Zwamel, Ahmed Hussein
    Abualigah, Laith
    INORGANIC CHEMISTRY COMMUNICATIONS, 2024, 170
  • [25] Design and synthesis of molecular scaffolds with anti-infective activity
    Liu, Junjia
    Bedell, T. Aaron
    West, Julian G.
    Sorensen, Erik J.
    TETRAHEDRON, 2016, 72 (25) : 3579 - 3592
  • [26] Novel 4-Thiazolidinone Derivatives as Anti-Infective Agents: Synthesis, Characterization, and Antimicrobial Evaluation
    Gupta, Amit
    Singh, Rajendra
    Sonar, Pankaj K.
    Saraf, Shailendra K.
    BIOCHEMISTRY RESEARCH INTERNATIONAL, 2016, 2016
  • [27] Synthesis, Analgesic, Anti-inflammatory and Antimicrobial Activities of Some Novel Pyrazoline Derivatives
    Sahu, S. K.
    Banerjee, M.
    Samantray, A.
    Behera, C.
    Azam, M. A.
    TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, 2008, 7 (02) : 961 - 968
  • [28] Anti-infective therapy of osteomyelitis
    Al-Nawas, B.
    MKG-CHIRURG, 2013, 6 (02): : 88 - 91
  • [29] NEPHROTOXICITY OF ANTI-INFECTIVE DRUGS
    ABRAMOWICZ, M
    EDELMANN, CM
    CLINICAL PEDIATRICS, 1968, 7 (07) : 389 - +
  • [30] PRINCIPLES OF ANTI-INFECTIVE THERAPY
    MONTGOMERY, EH
    KROEGER, DC
    DENTAL CLINICS OF NORTH AMERICA, 1984, 28 (03) : 423 - 432
12345