Low cytotoxicity rhodamine-based fluorescent probes for Fe(III) and their application in living cells

被引：21
|
作者：
Liu, Xiao-Jing [1 ]
Zhang, Ming [1 ]
Yang, Mei-Pan [1 ]
Li, Bo [1 ]
Cheng, Zhao [2 ]
Yang, Bing-Qin [1 ]
机构：
[1] Northwest Univ, Coll Chem & Mat Sci, Key Lab Synthet & Nat Funct Mol Chem, Minist Educ, Xian 710127, Shaanxi, Peoples R China
[2] Xian Med Univ, Sch Pharmaceut Sci, Xian 710021, Shaanxi, Peoples R China
来源：
TETRAHEDRON | 2015年 / 71卷 / 42期
基金：
中国国家自然科学基金;
关键词：
Rhodamine B; Fluorescent probe; Recognition; Low toxicity; Live cell imaging; IRON; CHEMOSENSOR; FE3+; IRON(III); COUMARIN;
D O I：
10.1016/j.tet.2015.08.031
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Two novel rhodamine-active probes G2 and R2 were designed and synthesized, which adopted a 1:1 binding stoichiometry and showed highly selective sensing for Fe3+ ions over other metal ions in EtOH-H2O (1:1, v/v, Tris-HCl pH=7.4) in the fluorescence and ultraviolet spectra. Cytotoxicity and bioimaging studies by PC12 and L929 indicated that the probes were low cytotoxic, cell permeable and suitable for detecting Fe3+ in living cells. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码：8194 / 8199
页数：6
相关论文
共 50 条
  • [31] Synthesis, Photophysical Properties, and Cytotoxicity of Rhodamine Based Fluorescent Probes
    Chang-Shik Harini Sampath Kumar
    Ki Hwan Choi
    Russian Journal of Bioorganic Chemistry, 2021, 47 : 691 - 699
  • [32] Rhodamine-based fluorescent polyacrylic nanoparticles: A highly selective and sensitive chemosensor for Fe (II) and Fe (III) cations in water
    Ghezelsefloo, Sara
    Rad, Jaber Keyvan
    Hajiali, Mahtab
    Mahdavian, Ali Reza
    JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, 2021, 9 (02):
  • [33] Two novel rhodamine-based fluorescent probes for the rapid and sensitive detection of Fe3+: Experimental and DFT calculations
    Wu, Zi-ying
    Xu, Zhong-yong
    Tan, Hui-ya
    Li, Xue
    Yan, Jin-wu
    Dong, Chang-zhi
    Zhang, Lei
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2019, 213 : 167 - 175
  • [34] Rhodamine-based 'turn-on' fluorescent probe for Cu(II) and its fluorescence imaging in living cells
    Tian, Mao-Zhong
    Hu, Ming-Ming
    Fan, Jiang-Li
    Peng, Xiao-Jun
    Wang, Jing-Yun
    Sun, Shi-Guo
    Zhang, Rong
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 23 (10) : 2916 - 2919
  • [35] A rhodamine-based fluorescent sensor for the highly selective and sensitive detection of mercury in aqueous solution and living cells
    Liu, Daying
    Qi, Jing
    Liu, Xiaoyan
    Cui, Zhigang
    Chang, Hexi
    Chen, Jiatong
    He, Huarui
    Yang, Guangming
    ANALYTICAL METHODS, 2014, 6 (11) : 3578 - 3581
  • [36] Rhodamine-based fluorescent and colorimetric sensor for zinc and its application in bioimaging
    Wechakorn, Kanokorn
    Suksen, Kanoknetr
    Piyachaturawat, Pawinee
    Kongsaeree, Palangpon
    SENSORS AND ACTUATORS B-CHEMICAL, 2016, 228 : 270 - 277
  • [37] Rhodamine-based cyclic hydrazide derivatives as fluorescent probes for selective and rapid detection of formaldehyde
    Kim, Sung Yeon
    Park, Sang-Hyun
    Lee, Chang-Hee
    Tae, Jinsung
    Shin, Injae
    RSC ADVANCES, 2022, 12 (35) : 22435 - 22439
  • [38] A Rhodamine-based fluorescent sensor for chromium ions and its application in bioimaging
    Xue-Mei Li
    Rui-Rui Zhao
    Yan Yang
    Xue Wei Lv
    Yu-Ling Wei
    Rui Tan
    Jun-Feng Zhang
    Ying Zhou
    ChineseChemicalLetters, 2017, 28 (06) : 1258 - 1261
  • [39] Rhodamine-based chemodosimeter for fluorescent determination of Hg2+ in 100% aqueous solution and in living cells
    Li, Dan
    Li, Chun-Yan
    Li, Yong-Fei
    Li, Zhi
    Xu, Fen
    ANALYTICA CHIMICA ACTA, 2016, 934 : 218 - 225
  • [40] A Rhodamine-based fluorescent sensor for chromium ions and its application in bioimaging
    Li, Xue-Mei
    Zhao, Rui-Rui
    Yang, Yan
    Lv, Xue Wei
    Wei, Yu-Ling
    Tan, Rui
    Zhang, Jun-Feng
    Zhou, Ying
    CHINESE CHEMICAL LETTERS, 2017, 28 (06) : 1258 - 1261
12345