Severe multiple organ failure as a consequence of diabetic ketoacidosis in an adolescent with new-onset type 1 diabetes: A case report

被引:2
|
作者
Modarelli, Rachel [1 ,4 ]
Brown, Lauren [2 ]
Boyd, Jenny [2 ]
Podd, Bradley [2 ]
Willis, Zachary [3 ]
Levenson, Amy [1 ]
机构
[1] Univ N Carolina, Sch Med, Div Pediat Endocrinol, Chapel Hill, NC USA
[2] Univ N Carolina, Sch Med, Div Pediat Crit Care Med, Chapel Hill, NC USA
[3] Univ N Carolina, Sch Med, Div Pediat Infect Dis, Chapel Hill, NC USA
[4] Univ N Carolina, Sch Med, Div Pediat Endocrinol, 127 Med Wing E,CB7039, Chapel Hill, NC 27599 USA
来源
关键词
Pediatric; diabetic ketoacidosis; multiple organ failure; CHILDREN; PREVALENCE; MUCORMYCOSIS; TRENDS;
D O I
10.1177/2050313X231190004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The initial presentation of pediatric diabetes is variable, making prompt diagnosis and treatment challenging. The overlap between type 1 and type 2 diabetes and presence of developmental delays can complicate diagnosis, resulting in delays and severe illness at presentation. Here we describe a case of a 13-year-old male with autism and attention deficit hyperactivity disorder who presented with severe diabetic ketoacidosis, multiple organ failure, and shock. Within 2 weeks of this initial presentation, he had further clinical decompensation due to an intestinal perforation. Cultures from resected gastrointestinal tissue grew mucormycosis, protracting his hospital stay and recovery. He was able to go home several months later with remarkable improvement. This case highlights the necessity of careful history taking and early testing, and how investigation for rare complications of diabetes is vital when patients do not improve as expected.
引用
收藏
页数:4
相关论文
共 50 条
  • [31] A Severe Case of Diabetic Ketoacidosis and New-Onset Type 1 Diabetes Mellitus Associated with Anti-Glutamic Acid Decarboxylase Antibodies Following Immunotherapy with Pembrolizumab
    Kedzior, Sonya K.
    Jacknin, Gabrielle
    Hudler, Andi
    Mueller, Scott W.
    Kiser, Tyree Heath
    AMERICAN JOURNAL OF CASE REPORTS, 2021, 22
  • [32] Diabetic ketoacidosis awareness and prevention for new onset Type 1 diabetes
    Chambers, Colleen
    JOURNAL OF PEDIATRIC NURSING-NURSING CARE OF CHILDREN & FAMILIES, 2022, 67 : 170 - 171
  • [33] The Relationship Between COVID-19 and the Development of Diabetic Ketoacidosis and New-Onset Type 1 Diabetes Mellitus
    Kellogg, Creighton
    Haenel, Louis C.
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2024, 16 (05)
  • [34] Increased Incidence of New-Onset Type 1 Diabetes and Diabetic Ketoacidosis in Children and Adolescents During Coronavirus Pandemic
    Luciano, Thais Milioni
    Machado, Gabriela Govea
    Oharomari, Mariana Peduti Hallah
    Antonini, Sonir
    Liberatore, Raphael Del Roio, Jr.
    Sarti, Mariana Tereza Alves
    HORMONE RESEARCH IN PAEDIATRICS, 2023, 96 : 199 - 199
  • [35] Subarachnoid and parenchymal haemorrhages as a complication of severe diabetic ketoacidosis in a preadolescent with new onset type 1 diabetes
    Finn, Bryan P.
    Power, Claire
    McSweeney, Niamh
    Breen, Dorothy
    Wyse, Gerald
    O'Connell, Susan M.
    PEDIATRIC DIABETES, 2018, 19 (08) : 1487 - 1491
  • [36] New-onset diabetes mellitus and diabetic ketoacidosis associated with olanzapine treatment
    Goldstein, LE
    Sporn, J
    Brown, S
    Kim, H
    Finkelstein, J
    Gaffey, GK
    Sachs, G
    Stern, TA
    PSYCHOSOMATICS, 1999, 40 (05) : 438 - 443
  • [38] Diabetic Ketoacidosis and Multiple Organ Failure Syndrome: A Case Study
    Bui Thao Phuong
    Vu Dung Chi
    Nguyen Khanh Ngoc
    Can Ngoc Thi Bich
    HORMONE RESEARCH IN PAEDIATRICS, 2016, 86 : 252 - 252
  • [39] New-onset type 1 diabetic ketoacidosis complicated by acute respiratory distress syndrome
    Landburg, P.
    de Sonnaville, J. J. J.
    Romijn, J. A.
    Juffermans, N. P.
    NETHERLANDS JOURNAL OF CRITICAL CARE, 2015, 22 (04): : 15 - 17