Severe multiple organ failure as a consequence of diabetic ketoacidosis in an adolescent with new-onset type 1 diabetes: A case report

被引:2
|
作者
Modarelli, Rachel [1 ,4 ]
Brown, Lauren [2 ]
Boyd, Jenny [2 ]
Podd, Bradley [2 ]
Willis, Zachary [3 ]
Levenson, Amy [1 ]
机构
[1] Univ N Carolina, Sch Med, Div Pediat Endocrinol, Chapel Hill, NC USA
[2] Univ N Carolina, Sch Med, Div Pediat Crit Care Med, Chapel Hill, NC USA
[3] Univ N Carolina, Sch Med, Div Pediat Infect Dis, Chapel Hill, NC USA
[4] Univ N Carolina, Sch Med, Div Pediat Endocrinol, 127 Med Wing E,CB7039, Chapel Hill, NC 27599 USA
来源
关键词
Pediatric; diabetic ketoacidosis; multiple organ failure; CHILDREN; PREVALENCE; MUCORMYCOSIS; TRENDS;
D O I
10.1177/2050313X231190004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The initial presentation of pediatric diabetes is variable, making prompt diagnosis and treatment challenging. The overlap between type 1 and type 2 diabetes and presence of developmental delays can complicate diagnosis, resulting in delays and severe illness at presentation. Here we describe a case of a 13-year-old male with autism and attention deficit hyperactivity disorder who presented with severe diabetic ketoacidosis, multiple organ failure, and shock. Within 2 weeks of this initial presentation, he had further clinical decompensation due to an intestinal perforation. Cultures from resected gastrointestinal tissue grew mucormycosis, protracting his hospital stay and recovery. He was able to go home several months later with remarkable improvement. This case highlights the necessity of careful history taking and early testing, and how investigation for rare complications of diabetes is vital when patients do not improve as expected.
引用
收藏
页数:4
相关论文
共 50 条
  • [21] A Case Report of New-Onset Type 1 Diabetes Mellitus with Diabetic Ketoacidosis, Deep Vein Thrombosis and Pulmonary Embolism-A Rare Presentation
    Chandratre, Sonal R.
    Babar, Ghufran
    DIABETES, 2011, 60 : A633 - A634
  • [22] Malignant hyperthermia and multi-organ failure in a mixed presentation of hyperosmolar hyperglycemic state and diabetic ketoacidosis in new-onset type 2 diabetes
    Bowden, S. A.
    Bigelow, A. M.
    Bakjaji, S.
    Fitch, J.
    Julian, J.
    Voss, J.
    McConnell, P. I.
    Kallash, M.
    Sivak, E. L.
    HORMONE RESEARCH IN PAEDIATRICS, 2024, 97 : 168 - 169
  • [23] New-onset Type 1 Diabetes Mellitus with Diabetic Ketoacidosis and Pancreatitis in a Patient with COVID-19
    Alfishawy, Mostafa
    Nassar, Mahmoud
    Mohamed, Mahmoud
    Fatthy, Moataz
    Elmessiery, Riem M.
    SCIENTIFIC AFRICAN, 2021, 13
  • [24] Cognitive Function Following Diabetic Ketoacidosis in Children With New-Onset or Previously Diagnosed Type 1 Diabetes
    Ghetti, Simona
    Kuppermann, Nathan
    Rewers, Arleta
    Myers, Sage R.
    Schunk, Jeff E.
    Stoner, Michael J.
    Garro, Aris
    Quayle, Kimberly S.
    Brown, Kathleen M.
    Trainor, Jennifer L.
    Tzimenatos, Leah
    DePiero, Andrew D.
    McManemy, Julie K.
    Nigrovic, Lise E.
    Kwok, Maria Y.
    Perry, Clinton S., III
    Olsen, Cody S.
    Casper, T. Charles
    Glaser, Nicole S.
    DIABETES CARE, 2020, 43 (11) : 2768 - 2775
  • [25] Diabetic ketoacidosis at the onset of type 1 diabetes
    Bowden, Sasigarn A.
    BMJ-BRITISH MEDICAL JOURNAL, 2011, 343
  • [26] A case of severe hypertriglyceridaemia complicating new-onset type 1 diabetes mellitus
    Belkhatir, Khadidja
    Lokulo-Sodipe, Oluwakemi
    Frohock, Anne-Marie
    Basu, Supriyo
    HORMONE RESEARCH IN PAEDIATRICS, 2021, 94 (SUPPL 1): : 255 - 255
  • [27] NEW-ONSET IDDM PRESENTING WITH DIABETIC-KETOACIDOSIS IN A PREGNANT ADOLESCENT
    SILLS, IN
    RAPAPORT, R
    DIABETES CARE, 1994, 17 (08) : 904 - 905
  • [28] New-onset type 1 diabetes complicated by diabetic ketoacidosis and severe sepsis requiring extracorporeal membrane oxygenation and kidney replacement therapy
    Asarani, Nurul Aliah Mohd
    Paddison, Justine
    Walker, Robert
    Downie, Michelle
    Wheeler, Benjamin J.
    JOURNAL OF DIABETES AND METABOLIC DISORDERS, 2021, 20 (01) : 1075 - 1079
  • [29] Lipemic serum in a child with new onset diabetes mellitus presenting in severe diabetic ketoacidosis: A case report
    Ponnuraj, Nirosha
    Panneerselvam, Reghupathy
    Rajendran, Monica D.
    JOURNAL OF DIABETOLOGY, 2024, 15 (01) : 115 - 118