Digital Microfluidic Lab-on-a-Chip on a TFT Glass Substrate Enabling Point-of-Care Testing

被引:5
|
作者
Xu, Yitong [1 ,2 ]
Wu, Weisheng [1 ,2 ]
Zhou, Zhongyi [1 ,2 ]
Su, Qiyi [1 ,2 ]
Liu, Xinghui [3 ]
Li, Weiwei [3 ]
Wang, Kai [4 ]
机构
[1] Sun Yat Sen Univ, Guangdong Prov Key Lab Display Mat & Technol, State Key Lab Optoelect Mat & Technol, Guangzhou 510275, Peoples R China
[2] Sun Yat Sen Univ, Sch Elect & Informat Technol, Guangzhou 510275, Peoples R China
[3] Shenzhen Chipwey Innovat Technol Co Ltd, Shenzhen 518100, Peoples R China
[4] Sun Yat Sen Univ, Guangdong Prov Key Lab Display Mat & Technol, State Key Lab Optoelect Mat & Technol, Sch Elect & Informat Technol, Guangzhou 510006, Peoples R China
基金
中国国家自然科学基金;
关键词
Digital microfluidic; disposable lab-on-a-chip; thin-film transistor; point-of-care testing; SENSORS;
D O I
10.1109/LED.2023.3299628
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
We report on a fully-integrated lab on a chip (LOC) on a thin-film transistor (TFT) glass substrate that integrates digital microfluidic array for droplet manipulation, on-chip resistive heater and temperature sensor for biochemical amplification reaction, on-chip optical sensor for fluorescence detection, and transimpedance preamplifier for signal amplification. The proposed LOC is manufactured in an industrial-standard TFT-LCD production line, making it very cost-effective and promising for disposable point-of-care testing (POCT) applications.
引用
收藏
页码:1500 / 1503
页数:4
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