The Diagnostic and Prognostic Potentials of TSPANs in Cancer: A Comprehensive Review

被引：0
|
作者：
Zhao, Kun [1 ,2 ]
Tian, Yijun [2 ]
Yang, Li [2 ,3 ,4 ]
Wang, Liping [5 ]
机构：
[1] Zhengzhou Univ, Dept Orthoped, Affiliated Hosp 1, Zhengzhou 450052, Henan, Peoples R China
[2] Zhengzhou Univ, Biol Cell Therapy Ctr, Affiliated Hosp 1, Zhengzhou 450052, Henan, Peoples R China
[3] Zhengzhou Univ, Sch Life Sci, Zhengzhou 450052, Henan, Peoples R China
[4] State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450040, Henan, Peoples R China
[5] Zhengzhou Univ, Dept Psychiat, Affiliated Hosp 1, Zhengzhou 450052, Henan, Peoples R China
来源：
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS | 2024年 / 38卷 / 01期
基金：
中国国家自然科学基金;
关键词：
tetraspanin; tumor marker; exosome; metastasis; TETRASPANIN-ENRICHED MICRODOMAINS; METASTASIS SUPPRESSOR GENE; TUMOR-CELL MOTILITY; BREAST-CANCER; COLORECTAL-CANCER; BETA-CATENIN; INTEGRIN ALPHA-3-BETA-1; MOLECULAR PATHWAYS; CD81; PROMOTES; CD151;
D O I：
10.23812/j.biol.regul.homeost.agents.20243801.7
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Tetraspanins are four transmembrane proteins that serve as a platform for interacting with a wide range of different molecules. It plays a crucial role in oncogenesis as well as in the metastasis in various cancer types. Numerous studies have investigated the use of various members of the tetraspanin family as prognostic markers and predictors of metastatic potential according to specific cancer types. This manuscript provides an overview of these advances, and their limitations, and suggests insights into future research areas for their clinical applications. Furthermore, the potential value of tetraspanin as a tumor-associated antigenic target will also be discussed in this review.
引用
收藏
页码：93 / 110
页数：18
相关论文
共 50 条
  • [21] The diagnostic and prognostic value of exosomal microRNAs in lung cancer: a systematic review
    Yang, Bingbing
    Xin, Xiaoqi
    Cao, Xiaoqing
    Nasifu, Lubanga
    Nie, Zhenlin
    He, Bangshun
    CLINICAL & TRANSLATIONAL ONCOLOGY, 2024, 26 (08): : 1921 - 1933
  • [22] Circulating MicroRNAs as Noninvasive Diagnostic and Prognostic Biomarkers in Pancreatic Cancer: A Review
    Imteyaz Ahmad Khan
    Anoop Saraya
    Journal of Gastrointestinal Cancer, 2023, 54 : 720 - 730
  • [23] Circulating MicroRNAs as Noninvasive Diagnostic and Prognostic Biomarkers in Pancreatic Cancer: A Review
    Khan, Imteyaz Ahmad
    Saraya, Anoop
    JOURNAL OF GASTROINTESTINAL CANCER, 2023, 54 (03) : 720 - 730
  • [24] Recent developments in diagnostic and prognostic biomarkers for colorectal cancer: a narrative review
    Giannopoulou, Nefeli
    Constantinou, Constantina
    ONCOLOGY, 2023, 101 (10) : 675 - 683
  • [25] Diagnostic and prognostic factors in patients with prostate cancer: a systematic review protocol
    Beyer, Katharina
    Moris, Lisa
    Lardas, Michael
    Haire, Anna
    Barletta, Francesco
    Scuderi, Simone
    Vradi, Eleni
    Gandaglia, Giorgio
    Omar, Muhammad Imran
    MacLennan, Steven
    Zong, Jihong
    Farahmand, Bahman
    Maclennan, Sara J.
    Devecseri, Zsuzsanna
    Asiimwe, Alex
    Collette, Laurence
    Bjartell, Anders
    Ndow, James
    Briganti, Alberto
    Van Hemelrijck, Mieke
    BMJ OPEN, 2021, 11 (02):
  • [26] Diagnostic and prognostic potentials of microRNA-27a in osteosarcoma
    Tang, Jie
    Zhao, Hui
    Cai, Haikang
    Wu, Haishan
    BIOMEDICINE & PHARMACOTHERAPY, 2015, 71 : 222 - 226
  • [27] Diagnostic, Prognostic, and Therapeutic Roles of Gut Microbiota in COVID-19: A Comprehensive Systematic Review
    Farsi, Yeganeh
    Tahvildari, Azin
    Arbabi, Mahta
    Vazife, Fateme
    Sechi, Leonardo A.
    Bonjar, Amir Hashem Shahidi
    Jamshidi, Parnian
    Nasiri, Mohammad Javad
    Mirsaeidi, Mehdi
    FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2022, 12
  • [28] Serum leptin level as a diagnostic and prognostic marker in infectious diseases and sepsis A comprehensive literature review
    Birlutiu, Victoria
    Boicean, Loredana Camelia
    MEDICINE, 2021, 100 (17) : E25720
  • [29] THE PROGNOSTIC VALUE OF QUALITY OF LIFE (QOL) RATINGS IN CANCER PATIENTS: A COMPREHENSIVE REVIEW
    Gotay, Carolyn C.
    QUALITY OF LIFE RESEARCH, 2004, 13 (09) : 1506 - 1506
  • [30] Prognostic factors in gallbladder cancer: a comprehensive systematic review and meta-analysis
    Hu, Xiaoqian
    Zeng, Di
    Wen, Ningyuan
    Wang, Yaoqun
    Lu, Jiong
    Li, Bei
    HEPATOBILIARY SURGERY AND NUTRITION, 2024,
12345