The role of perivascular adipose tissue-secreted adipocytokines in cardiovascular disease

被引：5
|
作者：
Cai, Meichao [1 ]
Zhao, Dongsheng [1 ]
Han, Xiao [1 ]
Han, Shuang [2 ]
Zhang, Wenxin [1 ]
Zang, Zhennan [1 ]
Gai, Chenchen [1 ]
Rong, Rong [1 ]
Gao, Tian [1 ]
机构：
[1] Shandong Univ Tradit Chinese Med, Sch Pharm, Jinan, Peoples R China
[2] Shanghai Jiao Tong Univ, Sch Med, Int Peace Matern & Child Hlth Hosp, Shanghai, Peoples R China
来源：
FRONTIERS IN IMMUNOLOGY | 2023年 / 14卷
关键词：
perivascular adipose tissue (PVAT); adipocytokines (adipokines); white adipose tissue (WAT); brown adipose tissue (BAT); cardiovascular disease; NITRIC-OXIDE SYNTHASE; INFLAMMATORY RESPONSE; ADIPONECTIN RECEPTORS; MESSENGER-RNA; EXPRESSION; OMENTIN; GROWTH; CELLS; LEPTIN; FAT;
D O I：
10.3389/fimmu.2023.1271051
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Perivascular adipose tissue and the vessel wall are connected through intricate bidirectional paracrine and vascular secretory signaling pathways. The secretion of inflammatory factors and oxidative products by the vessel wall in the diseased segment has the ability to influence the phenotype of perivascular adipocytes. Additionally, the secretion of adipokines by perivascular adipose tissue exacerbates the inflammatory response in the diseased vessel wall. Therefore, quantitative and qualitative studies of perivascular adipose tissue are of great value in the context of vascular inflammation and may provide a reference for the assessment of cardiovascular ischemic disease.
引用
收藏
页数：8
相关论文
共 50 条
  • [21] Perivascular Adipose Tissue -Orchestrat or of Cardiovascular Disturbances Sequel
    Aznauryan, A., V
    Navasardyan, G. A.
    Avagimyan, A. A.
    NEW ARMENIAN MEDICAL JOURNAL, 2022, 16 (04): : 107 - 114
  • [22] Perivascular adipose tissue in cardiovascular diseases-an update
    Grigoras, Adriana
    Amalinei, Cornelia
    Balan, Raluca Anca
    Giusca, Simona Eliza
    Caruntu, Irina Draga
    ANATOLIAN JOURNAL OF CARDIOLOGY, 2019, 22 (05): : 219 - 231
  • [23] Perivascular Adipose Tissue: the Sixth Man of the Cardiovascular System
    Chak Kwong Cheng
    Hamidah Abu Bakar
    Maik Gollasch
    Yu Huang
    Cardiovascular Drugs and Therapy, 2018, 32 : 481 - 502
  • [24] Mechanisms of Disease: adipocytokines and visceral adipose tissue—emerging role in nonalcoholic fatty liver disease
    Andreas Schäffler
    Jürgen Schölmerich
    Christa Büchler
    Nature Clinical Practice Gastroenterology & Hepatology, 2005, 2 : 273 - 280
  • [25] Mechanisms of Disease:: adipocytokines and visceral adipose tissue -: emerging role in nonalcoholic fatty liver disease
    Schäffler, A
    Schölmerich, J
    Büchler, C
    NATURE CLINICAL PRACTICE GASTROENTEROLOGY & HEPATOLOGY, 2005, 2 (06): : 273 - 280
  • [26] Perivascular Adipose Tissue: the Sixth Man of the Cardiovascular System
    Cheng, Chak Kwong
    Abu Bakar, Hamidah
    Gollasch, Maik
    Huang, Yu
    CARDIOVASCULAR DRUGS AND THERAPY, 2018, 32 (05) : 481 - 502
  • [27] ROLE OF PERIVASCULAR ADIPOSE TISSUE ON VASCULAR FUNCTION
    Gil-Ortega, Marta
    Galvez-Prieto, Beatriz
    Fernandez-Alfonso, Maria S.
    Somoza, Beatriz
    CLINICA E INVESTIGACION EN ARTERIOSCLEROSIS, 2009, 21 (02): : 71 - 77
  • [28] Role of perivascular adipose tissue as a calcium store
    Althobaiti, Musaad
    Garle, Michael
    Richard, Richard
    Randall, Michael
    BRITISH JOURNAL OF PHARMACOLOGY, 2020, 177 (11) : 2609 - 2609
  • [29] Mechanisms of Disease: adipocytokines and visceral adipose tissue—emerging role in intestinal and mesenteric diseases
    Andreas Schäffler
    Jürgen Schölmerich
    Christa Büchler
    Nature Clinical Practice Gastroenterology & Hepatology, 2005, 2 : 103 - 111
  • [30] Perivascular Adipose Tissue and Coronary Vascular Disease
    Owen, Meredith Kohr
    Noblet, Jillian N.
    Sassoon, Daniel J.
    Conteh, Abass M.
    Goodwill, Adam G.
    Tune, Johnathan D.
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2014, 34 (08) : 1643 - 1649
12345