Green Synthesis of Gold Nanoparticles Using Pithecellobium dulce Leaf Extract and Its Biological Activities

被引：2

作者：

Vincent, Jacob ^{[1
]}

Lekha, N. Chandra ^{[1
]}

机构：

[1] Kamaraj Coll, Dept Chem, Thoothukudi 628003, Tamil Nadu, India

来源：

CHEMICAL ENGINEERING & TECHNOLOGY | 2023年 / 46卷 / 07期

关键词：

Antibacterial activity; Anticancer activity; Gold nanoparticles; Pithecellobium dulce leaf extract; SILVER; BIOSYNTHESIS;

D O I：

10.1002/ceat.202100618

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Pithecellobium dulce leaf extract was used to synthesize gold nanoparticles (AuNPs) for the first time. This bio-synthesized novel material was investigated by UV-visible spectra, high-resolution transmission electron microscopy, powder diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, and energy-dispersive analysis by X-ray. Excellent antibacterial activity was revealed against Staphylococcus aureus and Escherichia coli. Significant antifungal activities by the AuNPs were also demonstrated. The analysis of AuNPs by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay proved 100 % toxic effect and the minimum value of half-maximal inhibitory concentration (IC50) indicates that it is safe to be used as drug in the medical field.

引用

页码：1424 / 1431

页数：8

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