LIGHTing CAR T in the tumor microenvironment

被引:0
|
作者
Liang, Yong [1 ]
Fu, Yang-Xin [1 ]
机构
[1] Tsinghua Univ, Sch Med, Dept Basic Med Sci, Beijing 100084, Peoples R China
关键词
THERAPY; CELLS;
D O I
10.1016/j.ymthe.2023.08.006
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
引用
收藏
页码:2570 / 2571
页数:2
相关论文
共 50 条
  • [41] T cells in tumor microenvironment
    Kiraz, Yagmur
    Baran, Yusuf
    Nalbant, Ayten
    TUMOR BIOLOGY, 2016, 37 (01) : 39 - 45
  • [42] A next generation inducible armored CAR to overcome the immunosuppressive tumor microenvironment and enhances cytotoxicity of CAR-T and TILs.
    Granger, David
    Harrasser, Micaela
    Evans, Rachel
    Muczynski, Vincent
    Chester, Kerry
    Nathwani, Amit C.
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16)
  • [43] Remodeling of Tumor Microenvironment by Tumor-Targeting Nanozymes Enhances Immune Activation of CAR T Cells for Combination Therapy
    Zhu, Lipeng
    Liu, Jie
    Zhou, Guangyu
    Liu, Tzu-Ming
    Dai, Yunlu
    Nie, Guangjun
    Zhao, Qi
    SMALL, 2021, 17 (43)
  • [44] Regulatory T cells and immune escape in HCC: understanding the tumor microenvironment and advancing CAR-T cell therapy
    Du, Guangtan
    Dou, Cunmiao
    Sun, Peng
    Wang, Shasha
    Liu, Jia
    Ma, Leina
    FRONTIERS IN IMMUNOLOGY, 2024, 15
  • [45] Overcoming the breast tumor microenvironment by targeting MDSCs through CAR-T cell therapy.
    Nalawade, Saisha Abhay
    Shafer, Paul
    Bajgain, Pradip
    McKenna, Katie
    Ali, Arushana
    Kelly, Lauren
    Joubert, Jarrett
    Watanabe, Norihiro
    Leen, Ann
    Parihar, Robin
    Valdes, Juan Fernando Vera
    Velez, Valentina Hoyos
    JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)
  • [46] Reshaping the tumor immune microenvironment to improve CAR-T cell-based cancer immunotherapy
    Xia, Xueting
    Yang, Zongxin
    Lu, Qisi
    Liu, Zhenyun
    Wang, Lei
    Du, Jinwen
    Li, Yuhua
    Yang, Dong-Hua
    Wu, Shaojie
    MOLECULAR CANCER, 2024, 23 (01)
  • [47] Nanoengineered CAR-T Biohybrids for Solid Tumor Immunotherapy with Microenvironment Photothermal-Remodeling Strategy
    Chen, Ze
    Pan, Hong
    Luo, Yingmei
    Yin, Ting
    Zhang, Baozhen
    Liao, Jianhong
    Wang, Mengmeng
    Tang, Xiaofan
    Huang, Guojun
    Deng, Guanjun
    Zheng, Mingbin
    Cai, Lintao
    SMALL, 2021, 17 (14)
  • [48] Live attenuated bacterium limits cancer resistance to CAR-T therapy by remodeling the tumor microenvironment
    Guo, Fengguang
    Das, Jugal K.
    Kobayashi, Koichi S.
    Qin, Qing-Ming
    Ficht, Thomas A.
    Alaniz, Robert C.
    Song, Jianxun
    De Figueiredo, Paul
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 (01)
  • [49] N glycosylation inhibition hinders immunosuppressive tumor microenvironment cells improving CAR T cell efficacy
    Sirini, Camilla
    Greco, Beatrice
    Balestrieri, Chiara
    Camisa, Barbara
    Falcone, Laura
    El Khoury, Rita
    Botrugno, Oronzina
    Giovannoni, Giulio
    Tonon, Giovanni
    Brunetto, Emanuela
    Cangi, Maria Giulia
    Pedica, Federica
    Bergamini, Alice
    Ciceri, Fabio
    Bonini, Chiara
    Casucci, Monica
    CANCER RESEARCH, 2024, 84 (06)
  • [50] Stressed target cancer cells drive nongenetic reprogramming of CAR T cells and solid tumor microenvironment
    Wang, Yufeng
    Drum, David L.
    Sun, Ruochuan
    Zhang, Yida
    Chen, Feng
    Sun, Fengfei
    Dal, Emre
    Yu, Ling
    Jia, Jingyu
    Arya, Shahrzad
    Jia, Lin
    Fan, Song
    Isakoff, Steven J.
    Kehlmann, Allison M.
    Dotti, Gianpietro
    Liu, Fubao
    Zheng, Hui
    Ferrone, Cristina R.
    Taghian, Alphonse G.
    DeLeo, Albert B.
    Ventin, Marco
    Cattaneo, Giulia
    Li, Yongxiang
    Jounaidi, Youssef
    Huang, Peigen
    Maccalli, Cristina
    Zhang, Hanyu
    Wang, Cheng
    Yang, Jibing
    Boland, Genevieve M.
    Sadreyev, Ruslan I.
    Wong, LaiPing
    Ferrone, Soldano
    Wang, Xinhui
    NATURE COMMUNICATIONS, 2023, 14 (01)