LIGHTing CAR T in the tumor microenvironment

被引:0
|
作者
Liang, Yong [1 ]
Fu, Yang-Xin [1 ]
机构
[1] Tsinghua Univ, Sch Med, Dept Basic Med Sci, Beijing 100084, Peoples R China
关键词
THERAPY; CELLS;
D O I
10.1016/j.ymthe.2023.08.006
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
引用
收藏
页码:2570 / 2571
页数:2
相关论文
共 50 条
  • [21] Cholesterol atlas of tumor microenvironment provides route to improved CAR-T therapy
    Chaves-Filho, Adriano B.
    Schulze, Almut
    CANCER CELL, 2023, 41 (07) : 1204 - 1206
  • [22] Enhancing CAR-T cell efficacy in solid tumors by targeting the tumor microenvironment
    Liu, Guangna
    Rui, Wei
    Zhao, Xueqiang
    Lin, Xin
    CELLULAR & MOLECULAR IMMUNOLOGY, 2021, 18 (05) : 1085 - 1095
  • [23] Improving CAR T cell function by reversing the immunosuppressive tumor microenvironment of pancreatic cancer
    Mohammed, Somala
    Sukumaran, Sujita
    Bajgain, Pradip
    Anurathapan, Usanarat
    Heslop, Helen E.
    Rooney, Cliona M.
    Brenner, Malcolm K.
    Leen, Ann M.
    Vera, Juan F.
    CANCER RESEARCH, 2015, 75
  • [24] Tumor Microenvironment Immunosuppression: A Roadblock to CAR T-Cell Advancement in Solid Tumors
    Johnson, Abigail
    Townsend, Michelle
    O'Neill, Kim
    CELLS, 2022, 11 (22)
  • [25] CAR-T: a potential gene carrier targeting solid tumor immune microenvironment
    Wang, Minjie
    Zhang, Chaocai
    Jiang, Xiaobing
    SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 6 (01)
  • [26] Lighting a Fire in the Tumor Microenvironment Using Oncolytic Immunotherapy
    Achard, Carole
    Surendran, Abera
    Wedge, Marie-Eve
    Ungerechts, Guy
    Bell, John
    Ilkow, Carolina S.
    EBIOMEDICINE, 2018, 31 : 17 - 24
  • [27] mRNA encoding a CAR specific stimulating protein (CSSP) mediates tumor metabolism regulated (TMR) CAR signaling for CAR-T expansion beyond the tumor microenvironment
    Vigant, Frederic
    Kundu, Anirban
    Betts, Michael
    Kerkar, Sid P.
    Frost, Gregory I.
    CANCER RESEARCH, 2024, 84 (06)
  • [28] Enhancing CAR-T cell metabolism to overcome hypoxic conditions in the brain tumor microenvironment
    Hatae, Ryusuke
    Kyewalabye, Keith
    Yamamichi, Akane
    Chen, Tiffany
    Phyu, Su
    Chuntova, Pavlina
    Nejo, Takahide
    Levine, Lauren S.
    Spitzer, Matthew H.
    Okada, Hideho
    JCI INSIGHT, 2024, 9 (07)
  • [29] Immunosuppression in tumor immune microenvironment and its optimization from CAR-T cell therapy
    Liu, Zaoqu
    Zhou, Zhaokai
    Dang, Qin
    Xu, Hui
    Lv, Jinxiang
    Li, Huanyun
    Han, Xinwei
    THERANOSTICS, 2022, 12 (14): : 6273 - 6290
  • [30] Oncolytic viral reshaping of the tumor microenvironment to promote CAR T cell therapy for glioblastoma.
    Brown, Christine E.
    Xella, Agata
    Hibbard, Jonathan C.
    Salvary, Vanessa
    Aguilar, Brenda
    Wagner, Jamie
    Dezube, Bruce
    Niss, Knut
    Bayless, Lynn
    Edinger, James
    Leavenworth, Jianmei
    Forman, Stephen J.
    Badie, Behnam
    Markert, James M.
    Cassady, Kevin A.
    CANCER RESEARCH, 2022, 82 (12)