"2+1B" Tricarbonyl Complexes of Technetium-99m and Rhenium with N,N '-Bidentate Ligands and Methyl 2-(Decylthio)-6-isocyanohexanoate

被引：2

作者：

Miroslavov, A. E. ^{[1
,2
,3
]}

Kuz'min, V. V. ^{[4
]}

Sakhonenkova, A. P. ^{[1
,2
,3
]}

Tyupina, M. Yu. ^{[1
,3
]}

Sidorenko, G. V. ^{[1
,3
]}

Kochergina, A. R. ^{[1
,3
]}

Polukeev, V. A. ^{[4
]}

机构：

[1] Khlopin Radium Inst, St Petersburg 194021, Russia

[2] St Petersburg State Univ, St Petersburg 199034, Russia

[3] Natl Res Nucl Univ MEPhI, Ozersk Inst Technol, Branch, Ozersk 456783, Chelyabinsk Obl, Russia

[4] AO Vekton, St Petersburg 192019, Russia

来源：

RADIOCHEMISTRY | 2023年 / 65卷 / 06期

基金：

俄罗斯科学基金会;

关键词：

technetium; rhenium; tricarbonyl complexes; bipyridine; phenanthroline; methyl 2-(decylthio)-6-isocyanohexanoate; lipophilicity; FATTY-ACID-METABOLISM; MYOCARDIAL-METABOLISM; N; N'-BIDENTATE LIGANDS; BETA-OXIDATION; BIODISTRIBUTION; TECHNETIUM; VALIDATION;

D O I：

10.1134/S1066362223060085

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

"2+1(B)" tricarbonyl complexes of the general formula [M(CO)(3)(N<^>N)CN(CH2)(4)CH(COOMe)SC10H21]-ClO4, where M = Tc-99m or Re, N<^>N = 2,2'-bipyridine (bipy) or 1,10-phenanthroline (phen), were prepared by the reaction of [M(CO)(3)(N<^>N)(MeOH)]ClO4 with methyl 2-(decylthio)-6-isocyanohexanoate in methanol. The rhenium complexes were isolated and characterized by H-1 NMR and IR spectroscopy. The formation of technetium-99m complexes was confirmed by HPLC. The lipophilicity of the technetium complexes was measured.

引用

页码：672 / 679

页数：8

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