"2+1B" Tricarbonyl Complexes of Technetium-99m and Rhenium with N,N '-Bidentate Ligands and Methyl 2-(Decylthio)-6-isocyanohexanoate

被引：2

作者：

Miroslavov, A. E. ^{[1
,2
,3
]}

Kuz'min, V. V. ^{[4
]}

Sakhonenkova, A. P. ^{[1
,2
,3
]}

Tyupina, M. Yu. ^{[1
,3
]}

Sidorenko, G. V. ^{[1
,3
]}

Kochergina, A. R. ^{[1
,3
]}

Polukeev, V. A. ^{[4
]}

机构：

[1] Khlopin Radium Inst, St Petersburg 194021, Russia

[2] St Petersburg State Univ, St Petersburg 199034, Russia

[3] Natl Res Nucl Univ MEPhI, Ozersk Inst Technol, Branch, Ozersk 456783, Chelyabinsk Obl, Russia

[4] AO Vekton, St Petersburg 192019, Russia

来源：

RADIOCHEMISTRY | 2023年 / 65卷 / 06期

基金：

俄罗斯科学基金会;

关键词：

technetium; rhenium; tricarbonyl complexes; bipyridine; phenanthroline; methyl 2-(decylthio)-6-isocyanohexanoate; lipophilicity; FATTY-ACID-METABOLISM; MYOCARDIAL-METABOLISM; N; N'-BIDENTATE LIGANDS; BETA-OXIDATION; BIODISTRIBUTION; TECHNETIUM; VALIDATION;

D O I：

10.1134/S1066362223060085

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

"2+1(B)" tricarbonyl complexes of the general formula [M(CO)(3)(N<^>N)CN(CH2)(4)CH(COOMe)SC10H21]-ClO4, where M = Tc-99m or Re, N<^>N = 2,2'-bipyridine (bipy) or 1,10-phenanthroline (phen), were prepared by the reaction of [M(CO)(3)(N<^>N)(MeOH)]ClO4 with methyl 2-(decylthio)-6-isocyanohexanoate in methanol. The rhenium complexes were isolated and characterized by H-1 NMR and IR spectroscopy. The formation of technetium-99m complexes was confirmed by HPLC. The lipophilicity of the technetium complexes was measured.

引用

页码：672 / 679

页数：8

共 50 条

[1] “2+1B” Tricarbonyl Complexes of Technetium-99m and Rhenium with N,N '-Bidentate Ligands and Methyl 2-(Decylthio)-6-isocyanohexanoate
A. E. Miroslavov
V. V. Kuz’min
A. P. Sakhonenkova
M. Yu. Tyupina
G. V. Sidorenko
A. R. Kochergina
V. A. Polukeev
Radiochemistry, 2023, 65 : 672 - 679
[2] "2+1B" Technetium-99m Tricarbonyl Complexes with N,N'-Bidentate Ligands and Methyl 14-Isocyano-3-methyltetradecanoate
Miroslavov, A. E.
Kuz'menko, P. M.
Tyupina, M. Yu.
Sakhonenkova, A. P.
Sidorenko, G. V.
Kochergina, A. R.
Krotov, S. A.
RADIOCHEMISTRY, 2024, 66 (04) : 522 - 530
[3] Erratum to: “2+1B” Technetium-99m Tricarbonyl Complexes with N,N'-Bidentate Ligands and Methyl 14-Isocyano-3-methyltetradecanoate
A. E. Miroslavov
P. M. Kuz’menko
M. Yu. Tyupina
A. P. Sakhonenkova
G. V. Sidorenko
A. R. Kochergina
S. A. Krotov
Radiochemistry, 2024, 66 (5) : 783 - 783
[4] “2+1” Rhenium and Technetium Tricarbonyl Complexes with N,N′-Bidentate Ligands and Methyl 11-Isocyanoundecanoate
A. E. Miroslavov
A. P. Sakhonenkova
M. Yu. Tyupina
G. V. Sidorenko
Russian Journal of General Chemistry, 2023, 93 : 327 - 331
[5] "2+1" Rhenium and Technetium Tricarbonyl Complexes with N,N′-Bidentate Ligands and Methyl 11-Isocyanoundecanoate
Miroslavov, A. E.
Sakhonenkova, A. P.
Tyupina, M. Yu.
Sidorenko, G. V.
RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2023, 93 (02) : 327 - 331
[6] 2+1 Rhenium Tricarbonyl Complexes with N,N′-Bidentate Ligands and Ethyl Isocyanoacetate: Synthesis, Structure, and Properties
M. Yu. Tyupina
A. E. Miroslavov
G. V. Sidorenko
V. V. Gurzhiy
A. P. Sakhonenkova
Russian Journal of General Chemistry, 2022, 92 : 69 - 78
[7] 2+1 Rhenium Tricarbonyl Complexes with N,N′-Bidentate Ligands and Ethyl Isocyanoacetate: Synthesis, Structure, and Properties
Tyupina, M. Yu
Miroslavov, A. E.
Sidorenko, G., V
Gurzhiy, V. V.
Sakhonenkova, A. P.
RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2022, 92 (01) : 69 - 78
[8] Synthesis of single isomer Technetium-99m and rhenium oxo complexes based on a N2S2 ligand.
Luyt, LG
Hunter, DH
JOURNAL OF NUCLEAR MEDICINE, 1998, 39 (05) : 218P - 219P
[9] Synthesis, characterization, and biodistribution of oxo complexes of Technetium-99m with biguanide and N1-substituted ligands
Neves, M
Gano, L
Ribeiro, MJ
Santos, AC
Marchi, A
Sawas-Dimopolou, C
de Lima, JJP
NUCLEAR MEDICINE AND BIOLOGY, 1999, 26 (01) : 79 - 83
[10] An N2S2 bifunctional chelator for technetium-99m and rhenium: Complexation, conjugation, and epimerization to a single isomer
Luyt, Leonard G.
Jenkins, Hilary A.
Hunter, Duncan H.
Bioconjugate Chemistry, 10 (03): : 470 - 479

← 1 2 3 4 5 →