Low-dose targeted alpha therapy induces strong anti-tumor effectiveness in combination with immune checkpoint inhibitors

被引:0
|
作者
Rodman, Samuel [1 ]
Cagle, Brianna [1 ]
Liu, Dijie [2 ]
Schultz, Michael [3 ]
Li, Mengshi [2 ]
机构
[1] Viewpoint Mol Targeting Inc, Coralville, IA USA
[2] Perspect Therapeut Inc, Seattle, WA USA
[3] Univ Iowa, Iowa City, IA 52242 USA
关键词
FDA APPROVAL; METASTATIC MELANOMA; NIVOLUMAB;
D O I
暂无
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
P-285
引用
收藏
页码:S261 / S262
页数:2
相关论文
共 50 条
  • [21] Wnt antagonists synergize with immune checkpoint inhibitors to enhance anti-tumor responses
    Ross, Jenny
    Hoey, Timothy
    Kapoun, Ann
    Lewicki, John
    Gurney, Austin
    Murriel, Christopher L.
    CANCER RESEARCH, 2018, 78 (13)
  • [22] Enhancement of anti-tumor efficacy of immune checkpoint blockade by alpha-TEA
    Redmond, William L.
    Kasiewicz, Melissa J.
    Akporiaye, Emmanuel T.
    FRONTIERS IN IMMUNOLOGY, 2023, 14
  • [23] Enhancing the therapeutic efficacy of immune checkpoint inhibition and targeted therapy using anti-tumor antibodies in mouse melanoma
    Perez-Lorenzo, R.
    Erjavec, S.
    Clynes, R.
    Christiano, A. M.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2018, 138 (05) : S205 - S205
  • [24] Chemotherapy reinforces anti-tumor immune response and enhances clinical efficacy of immune checkpoint inhibitors
    Zhang, Lin
    Zhou, Chao
    Zhang, Songou
    Chen, Xiaozhen
    Liu, Jian
    Xu, Fangming
    Liang, Wenqing
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [25] Targeted Alpha-Particle Radiotherapy and Immune Checkpoint Inhibitors Induces Cooperative Inhibition on Tumor Growth of Malignant Melanoma
    Li, Mengshi
    Liu, Dijie
    Lee, Dongyoul
    Cheng, Yinwen
    Baumhover, Nicholas J.
    Marks, Brenna M.
    Sagastume, Edwin A.
    Ballas, Zuhair K.
    Johnson, Frances L.
    Morris, Zachary S.
    Schultz, Michael K.
    CANCERS, 2021, 13 (15)
  • [26] Combination therapy of 211At-labeled RGD peptide with immune checkpoint blockade to enhance anti-tumor efficacy
    Echigo, H.
    Munekane, M.
    Fuchigami, T.
    Washiyama, K.
    Mishiro, K.
    Wakabayashi, H.
    Takahashi, K.
    Kinuya, S.
    Ogawa, K.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2024, 51 : S314 - S315
  • [27] Calcineurin inhibitors in steroid- and anti-tumor necrosis factor-alpha-refractory immune checkpoint inhibitor colitis
    Zhang, E.
    Kiely, C.
    Sandanayake, N.
    Tattersall, S.
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2020, 35 : 128 - 129
  • [28] Anti-tumor Immunity and Improved Survival with Combination of Immune Checkpoint Blockade and Local Chemotherapy
    Green, J.
    Rudensky, A.
    Ariyan, C. E.
    ANNALS OF SURGICAL ONCOLOGY, 2015, 22 : S113 - S113
  • [29] Prospect of Immunotherapy for Glioblastoma: Tumor Vaccine, Immune Checkpoint Inhibitors and Combination Therapy
    Ishikawa, Eiichi
    Yamamoto, Tetsuya
    Matsumura, Akira
    NEUROLOGIA MEDICO-CHIRURGICA, 2017, 57 (07) : 321 - 330
  • [30] Biomarkers of related driver genes predict anti-tumor efficacy of immune checkpoint inhibitors
    Jiang, Shuai
    Geng, Shuai
    Luo, Xinyu
    Zhang, Can
    Yu, Yang
    Cheng, Mengfei
    Zhang, Shuo
    Shi, Ning
    Dong, Mei
    FRONTIERS IN IMMUNOLOGY, 2022, 13