Aggressive Angiomyxoma of the Vulva: Which Is the Best Management Strategy? Description of a Case Report and Review of Literature of the Last Ten Years

被引:12
|
作者
Gulino, Ferdinando Antonio [1 ]
Gulisano, Marianna [1 ]
Ettore, Carla [1 ]
Giorlandino, Alexandra [2 ]
Russo, Emanuele [1 ]
Ettore, Giuseppe [1 ]
机构
[1] Azienda Rilievo Nazl & Alta Specializzaz ARNAS Gar, Dept Obstet & Gynaecol, I-95124 Catania, Italy
[2] Azienda Rilievo Nazl & Alta Specializzaz ARNAS Gar, Dept Pathol Anat, I-95124 Catania, Italy
关键词
aggressive angiomyxoma; mesenchymal tumour; genital tumour; vulvar lesion; ULTRASOUND; VAGINA; MASS;
D O I
10.3390/jcm12051726
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Aggressive angiomyxoma is a rare mesenchymal tumour of the genital tract with a high incidence in women of reproductive age. The aim of our work is to understand which is the best management strategy for this condition, starting from the description of a rare case report up to the performance of a narrative review of the literature. Methods: We report a case of a 46-year-old woman who came to our attention because of the growth of a 10-centimetre pedunculated, non-soft, non-tender mass of the left labium majus. She underwent surgical excision, and the histologic diagnosis was aggressive angiomyxoma. Due to a lack of tumour-free margins, radicalization surgery was carried out after three months. A review of the literature of the last ten years was performed following the PRISMA statement on MEDLINE (PubMed). We obtained data from twenty-five studies describing thirty-three cases. Results: Aggressive angiomyxoma is characterized by a high recurrence rate of between 36 and 72% after surgery. There is no universal consensus about hormonal therapy, and most studies (85%) describe surgical excision followed by only clinical and radiological follow-up. Conclusion: Wide surgical excision is the gold-standard treatment for aggressive angiomyxoma, succeeded by either clinical or radiological (ultrasound or MRI) follow-up.
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页数:11
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