Aggressive Angiomyxoma of the Vulva: Which Is the Best Management Strategy? Description of a Case Report and Review of Literature of the Last Ten Years

被引:12
|
作者
Gulino, Ferdinando Antonio [1 ]
Gulisano, Marianna [1 ]
Ettore, Carla [1 ]
Giorlandino, Alexandra [2 ]
Russo, Emanuele [1 ]
Ettore, Giuseppe [1 ]
机构
[1] Azienda Rilievo Nazl & Alta Specializzaz ARNAS Gar, Dept Obstet & Gynaecol, I-95124 Catania, Italy
[2] Azienda Rilievo Nazl & Alta Specializzaz ARNAS Gar, Dept Pathol Anat, I-95124 Catania, Italy
关键词
aggressive angiomyxoma; mesenchymal tumour; genital tumour; vulvar lesion; ULTRASOUND; VAGINA; MASS;
D O I
10.3390/jcm12051726
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Aggressive angiomyxoma is a rare mesenchymal tumour of the genital tract with a high incidence in women of reproductive age. The aim of our work is to understand which is the best management strategy for this condition, starting from the description of a rare case report up to the performance of a narrative review of the literature. Methods: We report a case of a 46-year-old woman who came to our attention because of the growth of a 10-centimetre pedunculated, non-soft, non-tender mass of the left labium majus. She underwent surgical excision, and the histologic diagnosis was aggressive angiomyxoma. Due to a lack of tumour-free margins, radicalization surgery was carried out after three months. A review of the literature of the last ten years was performed following the PRISMA statement on MEDLINE (PubMed). We obtained data from twenty-five studies describing thirty-three cases. Results: Aggressive angiomyxoma is characterized by a high recurrence rate of between 36 and 72% after surgery. There is no universal consensus about hormonal therapy, and most studies (85%) describe surgical excision followed by only clinical and radiological follow-up. Conclusion: Wide surgical excision is the gold-standard treatment for aggressive angiomyxoma, succeeded by either clinical or radiological (ultrasound or MRI) follow-up.
引用
收藏
页数:11
相关论文
共 50 条
  • [31] Is It Possible to Diagnose Preoperatively a Tubal Ectopic Hydatidiform Molar Pregnancy? Description of a Case Report and Review of the Literature of the Last Ten Years
    D'Asta, Marco
    La Ferrera, Nicolo
    Gulino, Ferdinando Antonio
    Ettore, Carla
    Ettore, Giuseppe
    JOURNAL OF CLINICAL MEDICINE, 2022, 11 (19)
  • [32] Maxillary aggressive angiomyxoma showing ineffective to radiotherapy: a rare case report and review of literature
    Wang, Zhaoling
    Liu, Ying
    Yang, Lu
    Gu, Ling
    He, Yuhong
    Huang, Diyan
    Zhu, Guoxiong
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2015, 8 (01): : 1063 - 1067
  • [33] Incidental para-ureteral aggressive angiomyxoma: a rare case report and literature review
    Ming Liu
    Ting-Shuai Zhai
    Xiao-Feng Zhao
    Li-Jin Feng
    Xin-Sheng Lyu
    Lan-Ting Hu
    Zheng-Xin Wang
    Wei-Guo Ma
    Jian Zhang
    Xiao Chen
    Bin-Jie Su
    Xu-Dong Yao
    Jing-Yi Lu
    Lin Ye
    BMC Urology, 20
  • [34] Incidental para-ureteral aggressive angiomyxoma: a rare case report and literature review
    Liu, Ming
    Zhai, Ting-Shuai
    Zhao, Xiao-Feng
    Feng, Li-Jin
    Lyu, Xin-Sheng
    Hu, Lan-Ting
    Wang, Zheng-Xin
    Ma, Wei-Guo
    Zhang, Jian
    Chen, Xiao
    Su, Bin-Jie
    Yao, Xu-Dong
    Lu, Jing-Yi
    Ye, Lin
    BMC UROLOGY, 2020, 20 (01)
  • [35] Genital Prolapse in Pregnant Woman as a Presentation of Aggressive Angiomyxoma: Case Report and Literature Review
    Espejo-Reina, Maria Pilar
    Prieto-Moreno, Miriam
    De-Miguel-Blanc, Marina
    Perez-Martinez, Daniela Maria
    Jimenez-Lopez, Jesus Salvador
    Monis-Rodriguez, Susana
    MEDICINA-LITHUANIA, 2022, 58 (01):
  • [36] AGGRESSIVE ANGIOMYXOMA OF THE FEMALE PELVIS AND PERINEUM - CASE-REPORT AND LITERATURE-REVIEW
    MASCARENHAS, L
    KNAGGS, J
    CLARK, J
    ELIOT, B
    AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1993, 169 (03) : 555 - 556
  • [37] Importance of accurate preoperative diagnosis in the management of aggressive angiomyxoma: report of three cases and review of the literature
    A. Wiser
    J. Korach
    W. H. Gotlieb
    E. Fridman
    S. Apter
    G. Ben-Baruch
    Abdominal Imaging, 2006, 31 : 383 - 386
  • [38] Fine-needle aspiration cytology findings in a case of aggressive angiomyxoma: A case report and review of the literature
    Layfield, LJ
    Dodd, LG
    DIAGNOSTIC CYTOPATHOLOGY, 1997, 16 (05) : 425 - 429
  • [39] Importance of accurate preoperative diagnosis in the management of aggressive angiomyxoma: report of three cases and review of the literature
    Wiser, A.
    Korach, J.
    Gotlieb, W. H.
    Fridman, E.
    Apter, S.
    Ben-Baruch, G.
    ABDOMINAL IMAGING, 2006, 31 (03): : 383 - 386
  • [40] Aggressive angiomyxoma of the cervix mimicking a cervical polyp. Report of an unusual case and review of the literature
    Hadjileontis, C.
    Paplomata, E.
    Balaxis, D.
    Kafanas, A.
    VIRCHOWS ARCHIV, 2009, 455 : 288 - 288