Three new chromanes and one new flavone C-glycoside from Mallotus apelta

被引:4
|
作者
Nguyen Hoang Anh [1 ,2 ]
Duong Thi Hai Yen [3 ]
Nguyen The Cuong [4 ]
Bui Huu Tai [1 ,3 ]
Pham Hai Yen [1 ]
Pham The Chinh [2 ]
Pham Van Cuong [3 ]
Nguyen Hoai Nam [3 ]
Phan Van Kiem [1 ,3 ]
Su-Hyeon Cho [5 ]
Park, SeonJu [5 ]
Nguyen Xuan Nhiem [1 ,3 ]
机构
[1] Vietnam Acad Sci & Technol VAST, Grad Univ Sci & Technol, Hanoi 10072, Vietnam
[2] Thai Nguyen Univ Sci, Fac Chem, Thai Nguyen 24118, Vietnam
[3] VAST, Inst Marine Biochem, 18 Hoang Quoc Viet, Hanoi 10072, Vietnam
[4] VAST, Inst Ecol & Biol Resources, Hanoi 10072, Vietnam
[5] Korea Basic Sci Inst, Chuncheon Ctr, 1 Kangwondaehak Gil, Chuncheon Si 24341, Gangwon Do, South Korea
关键词
Mallotus apelta; Euphorbiaceae; chromane; flavone C-glycoside; malloapelta; malloflavoside;
D O I
10.1080/10286020.2022.2051494
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Three new chromanes, malloapeltas J-L (1-3), and one new flavone C-glycoside, malloflavoside (4), together with four known compounds, apigenin 6-C-beta-D-xylopyranosyl-8-C-alpha-L-arabinopyranoside (5), apigenin 6-C-beta-D-glucopyranosyl-8-C-alpha-L-arabinopyranoside (6), apigenin 7-O-beta-D-apiofuranosyl-(1 -> 2)-beta-D-glucopyranoside (7), and acantrifoside E (8) were isolated from the methanol extract of the leaves of Mallotus apelta. Their chemical structures were determined using spectroscopic methods, including 1D, 2D NMR, and HR-ESI-MS methods. All the isolated compounds were evaluated their cytotoxic activity against human prostate cancer (PC-3) and human breast cancer (MCF-7) cells, but none of them showed cytotoxicities on both human cancer cell lines.
引用
收藏
页码:18 / 26
页数:9
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