Treatment of diabetic neuropathy is a dif-ficult cJinical problem.In this paper,clinicalexperience on managing 120 newly discovered,untreated,noninsulin dependent cases is pre-sented.Besides strict control of diabetes,thetherapeutic effect of different drugs includingthe vitamin B group,myoinositol,carbamaze-pine,etc for neurologic manifestations is in-vestigated.No statistical difference was foundbetween groups with or without drug therapy.So the strict control of diabetes with attenua-tion of hyperglycemia has been considered thesole reliable factor for the effective therapy ofneuropathy.Motor nerve conduction velocitywas restored to a certain extent in differentperipheral nerves indicating that early func-tional nerve damage is reversible on diabetictherapy.Neurogenie bladder and other auto-nomic dysfunction can also be remitted.Whileboth peripheral and autonomic neuropathy canbe improved on diabetic control,early diagno-sis and treatment are the key to obtaining goodtherapeutic effect.
机构:
Univ Michigan Hlth Syst, Ann Arbor, MI 48109 USA
Univ Michigan, Coll Pharm, 428 Church St, Ann Arbor, MI 48109 USAUniv Michigan Hlth Syst, Ann Arbor, MI 48109 USA
Farhat, Nada M.
Yezback, Krista L.
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Univ Michigan, Canton Hlth Ctr, Canton, MI USAUniv Michigan Hlth Syst, Ann Arbor, MI 48109 USA