Studies on repairing of hemisected thoracic spinal cord of adult rats by using a chitosan tube filled with alginate fibers

被引：1
|
作者：
LI Xiaoguang
Department of Bioengineering
National Center of Biomedical Analysis
机构：
来源：
ProgressinNaturalScience | 2006年 / 10期
基金：
中国国家自然科学基金;
关键词：
spinal cord injury; regeneration; function recovery; chitosan; alginate; behavioral evaluation;
D O I：
暂无
中图分类号：
Q95-33 [动物学实验（实验动物学）、动物学技术];
学科分类号：
071002 ;
摘要：
A chitosan tube filled with alginate fibers was implanted into the injured spinal cord of a rat for repairing the damaged tissue. Twelve months after the operation, the morphological observation demonstrated that this chitosan tube could induce regeneration of myelinated and non-myelinated axons and blood vessels. The Basso-Beattie-Bresnahan (BBB) behavioral evaluation confirmed that the implants played a key role in the long-term restoration of rats motor functions. It is a promising start in the treatment of the patients with the injury of the spinal cord.
引用
收藏
页码：1051 / 1055
页数：5
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