In situ bioprinting: Tailored printing strategies for regenerative medicine

被引:0
|
作者
Hu, Chengwei [1 ,2 ]
Wang, Chenmin [1 ]
Bian, Shaoquan [1 ]
Qi, Weichen [3 ,4 ]
Liu, Bo [1 ]
Wang, Liangliang [1 ]
Wen, Chunyi [5 ]
Wu, Jun [3 ,6 ]
Lu, William W. [1 ,3 ]
Zhao, Xiaoli [1 ,2 ]
机构
[1] Chinese Acad Sci, Inst Biomed & Biotechnol, Shenzhen Inst Adv Technol, Res Ctr Human Tissues & Organs Degenerat, Shenzhen, Guangdong, Peoples R China
[2] Univ Chinese Acad Sci, Beijing, Peoples R China
[3] Univ Hong Kong, Fac Med, Dept Orthopaed & Traumatol, Hong Kong, Peoples R China
[4] Shanghai Jiao Tong Univ, Ruijin Hosp, Shanghai Inst Traumatol & Orthoped, Sch Med,Dept Orthoped,Shanghai Key Lab Prevent &, Shanghai, Peoples R China
[5] Hong Kong Polytech Univ, Fac Engn, Dept Biomed Engn, Hong Kong, Peoples R China
[6] Univ Hong Kong, Engn Technol Res Ctr Orthopaed Trauma Repair, Dept Orthopaed & Traumatol,Shenzhen Hosp, Shenzhen Key Lab Innovat Technol Orthopaed Trauma, Shenzhen, Guangdong, Peoples R China
关键词
Bioprinting; In situ bioprinting; Tissue regeneration; Bioinks; Handheld bioprinter; ALGINATE HYDROGELS; TISSUE; BONE; SCAFFOLDS;
D O I
10.36922/ijb.3366
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
In recent years, three-dimensional (3D) bioprinting has emerged as a revolutionary biological manufacturing technology. Despite significant progress, current bioprinting technologies face critical barriers, such as the need for in vitro maturation of printed tissues before implantation and challenges of prefabricated structures not matching the defect shapes. In situ bioprinting has been introduced to address these challenges by printing customized structures to the wound shape via direct deposition of biological inks at the tissue interface. This paper reviews strategies to optimize printing performance for enhanced tissue repair and analyzes the advantages, challenges, and future directions of in situ bioprinting technologies.
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收藏
页数:21
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