Synthesis of C-N or C-C Spiroindolines via Rearrangement Coupling Reaction

被引：1

作者：

Liu, Xiaoling ^{[1
]}

Qiao, Panpan ^{[1
]}

Chen, Hui ^{[1
]}

Gao, Yu ^{[1
]}

Chen, Haijun ^{[1
]}

机构：

[1] Fuzhou Univ, Coll Chem, Key Lab Mol Synth & Funct Discovery, Fuzhou 350116, Fujian, Peoples R China

来源：

ORGANIC LETTERS | 2024年 / 26卷 / 45期

基金：

中国国家自然科学基金;

关键词：

TETRAHYDRO-BETA-CARBOLINES; ENANTIOSELECTIVE SYNTHESIS; SPIROOXINDOLES; CONSTRUCTION; SCAFFOLDS; ACCESS;

D O I：

10.1021/acs.orglett.4c03644

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Herein, we report a general approach to effectively construct C-N or C-C spiroindolines using tetrahydro-beta-carbolines as starting materials via a rearrangement coupling reaction. This method is characterized by its operational simplicity and mild conditions. Notably, a wide range of anilines and indoles are suitable for this intermolecular coupling, yielding the corresponding C-N or C-C spiroindolines in good to excellent yields.

引用

页码：9759 / 9763

页数：5

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