Synthesis of C-N or C-C Spiroindolines via Rearrangement Coupling Reaction

被引：1
|
作者：
Liu, Xiaoling [1 ]
Qiao, Panpan [1 ]
Chen, Hui [1 ]
Gao, Yu [1 ]
Chen, Haijun [1 ]
机构：
[1] Fuzhou Univ, Coll Chem, Key Lab Mol Synth & Funct Discovery, Fuzhou 350116, Fujian, Peoples R China
来源：
ORGANIC LETTERS | 2024年 / 26卷 / 45期
基金：
中国国家自然科学基金;
关键词：
TETRAHYDRO-BETA-CARBOLINES; ENANTIOSELECTIVE SYNTHESIS; SPIROOXINDOLES; CONSTRUCTION; SCAFFOLDS; ACCESS;
D O I：
10.1021/acs.orglett.4c03644
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Herein, we report a general approach to effectively construct C-N or C-C spiroindolines using tetrahydro-beta-carbolines as starting materials via a rearrangement coupling reaction. This method is characterized by its operational simplicity and mild conditions. Notably, a wide range of anilines and indoles are suitable for this intermolecular coupling, yielding the corresponding C-N or C-C spiroindolines in good to excellent yields.
引用
收藏
页码：9759 / 9763
页数：5
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