The evolutionary history of metastatic pancreatic neuroendocrine tumors reveals a therapy driven route to high-grade transformation

被引:0
|
作者
Backman, S. [1 ]
Botling, J. [2 ,3 ]
Nord, H. [4 ]
Ghosal, S. [5 ]
Stalberg, P. [1 ]
Juhlin, C. C. [6 ]
Hellman, P. [1 ]
Skogseid, B. [7 ]
Pacak, K. [5 ]
Mollazadegan, K. [7 ]
Akerstrom, T. [1 ]
Crona, J. [7 ]
机构
[1] Uppsala Univ, Dept Surg Sci, Uppsala, Sweden
[2] Uppsala Univ, Uppsala, Sweden
[3] Univ Gothenburg, Gothenburg, Sweden
[4] Uppsala Univ, Dept Immunol Genet & Pathol, Uppsala, Sweden
[5] NIH, Sect Med Neuroendocrinol, Bethesda, MD USA
[6] Karolinska Inst, Dept Oncol Pathol, Stockholm, Sweden
[7] Uppsala Univ, Dept Med Sci, Uppsala, Sweden
关键词
pancreatic neuroendocrine tumor; tumor evolution; alkylating chemotherapy; treatment resistance;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A03
引用
收藏
页码:20 / 20
页数:1
相关论文
共 50 条
  • [41] Clinicopathological Features of Primary Neuroendocrine Tumors of Gastrointestinal/Pancreatobiliary Tract With Emphasis on High-Grade (Grade 3) Well-Differentiated Neuroendocrine Tumors
    Hashmi, Atif A.
    Ali, Javaria
    Yaqeen, Syed Rafay
    Ahmed, Omer
    Asghar, Ishaq Azeem
    Irfan, Muhammad
    Asif, Muhammad Ghani
    Edhi, Muhammad M.
    Hashmi, Shumaila
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2021, 13 (01)
  • [42] High-Grade Neuroendocrine Transformation of Post-Treatment Conventional Breast Carcinoma
    Weisman, Paul
    Rekhtman, Natasha
    Corben, Adriana
    Dickler, Maura
    Pietanza, Maria
    Tan, Lee
    LABORATORY INVESTIGATION, 2015, 95 : 73A - 73A
  • [43] High-Grade Neuroendocrine Transformation of Post-Treatment Conventional Breast Carcinoma
    Weisman, Paul
    Rekhtman, Natasha
    Corben, Adriana
    Dickler, Maura
    Pretanza, Maria
    Tan, Lee
    MODERN PATHOLOGY, 2015, 28 : 73A - 73A
  • [44] Are Serum Markers Useful In Patients With Resected Pulmonary High-Grade Neuroendocrine Tumors?
    Nakagawa, K.
    Yotsukura, M.
    Yoshida, Y.
    Watanabe, S.
    JOURNAL OF THORACIC ONCOLOGY, 2021, 16 (10) : S1191 - S1191
  • [45] Phase II study of pembrolizumab for high-grade neuroendocrine tumors of the cervix and vulva
    Frumovitz, M.
    Westin, S. N.
    Yap, T.
    Rodon, J. A.
    Karp, D. D.
    Abonofal, A.
    Jazaeri, A. A.
    Naing, A.
    GYNECOLOGIC ONCOLOGY, 2020, 159 : 23 - 23
  • [46] Radiation Therapy for High-Grade Neuroendocrine Carcinoma of the Rectum and Anal Canal
    Voong, K.
    Rashid, A.
    Crane, C. H.
    Minsky, B. D.
    Krishnan, S.
    Yao, J. C.
    Wolff, R. A.
    Skibber, J. M.
    Feig, B. W.
    Chang, G. J.
    Das, P.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2014, 90 : S394 - S394
  • [47] Long term outcomes of neuroendocrine carcinomas (high-grade neuroendocrine tumors) of the colon, rectum, and anal canal
    Aytac, E.
    Ozdemir, Y.
    Ozuner, G.
    JOURNAL OF VISCERAL SURGERY, 2014, 151 (01) : 3 - 7
  • [48] Genetic characterization of primary and metastatic high-grade serous ovarian cancer tumors reveals distinct features associated with survival
    Kotnik, Emilee N.
    Mullen, Mary M.
    Spies, Nicholas C.
    Li, Tiandao
    Inkman, Matthew
    Zhang, Jin
    Martins-Rodrigues, Fernanda
    Hagemann, Ian S.
    McCourt, Carolyn K.
    Thaker, Premal H.
    Hagemann, Andrea R.
    Powell, Matthew A.
    Mutch, David G.
    Khabele, Dineo
    Longmore, Gregory D.
    Mardis, Elaine R.
    Maher, Christopher A.
    Miller, Christopher A.
    Fuh, Katherine C.
    COMMUNICATIONS BIOLOGY, 2023, 6 (01)
  • [49] Genetic characterization of primary and metastatic high-grade serous ovarian cancer tumors reveals distinct features associated with survival
    Emilee N. Kotnik
    Mary M. Mullen
    Nicholas C. Spies
    Tiandao Li
    Matthew Inkman
    Jin Zhang
    Fernanda Martins-Rodrigues
    Ian S. Hagemann
    Carolyn K. McCourt
    Premal H. Thaker
    Andrea R. Hagemann
    Matthew A. Powell
    David G. Mutch
    Dineo Khabele
    Gregory D. Longmore
    Elaine R. Mardis
    Christopher A. Maher
    Christopher A. Miller
    Katherine C. Fuh
    Communications Biology, 6
  • [50] Determination of a Prognostic Classification System in Metastatic Grade 1 and 2 Pancreatic Neuroendocrine Tumors (PNETs)
    Fernandez Plana, J.
    Bestanti, C.
    Thirlwell, C.
    Campana, D.
    Handkiewicz Junak, D.
    De Herder, W.
    Costa, F.
    Moneon Getino, A.
    NEUROENDOCRINOLOGY, 2014, 99 (3-4) : 246 - 246