Hidradenitis suppurativa pathogenesis: Extrinsic factors

被引：1

作者：

Nielsen, Valdemar Wendelboe ^{[2
]}

Thomsen, Simon Francis ^{[1
,3
]}

Naik, Haley B. ^{[4
]}

机构：

[1] Copenhagen Univ Hosp Bispebjerg & Frederiksberg, Dept Dermatovenereol, Copenhagen, Denmark

[2] Copenhagen Univ Hosp Bispebjerg & Frederiksberg, Wound Healing Ctr, Copenhagen, Denmark

[3] Univ Copenhagen, Dept Biomed Sci, Copenhagen, Denmark

[4] Univ Calif San Francisco, Dept Dermatol, 1701 Divisadero St,Suite 4-20, San Francisco, CA 94115 USA

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2024年 / 91卷 / 06期

关键词：

extrinsic; hidradenitis suppurativa; mechanical stress; pathogenesis; BACTERIAL BIOFILM; MECHANICAL-STRESS; SKIN MICROBIOME; DIET; PREVALENCE; SMOKING; LESIONS; WEIGHT;

D O I：

10.1016/j.jaad.2024.07.1524

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

While genetic predisposition and immune dysregulation are recognized as key contributors to the development of hidradenitis suppurativa, accumulating research points to the influence of extrinsic factors in the pathogenesis of this condition. This review explores the roles of mechanical stress, altered skin and gut microbiome, tobacco smoking, diet, and paradoxical drug reactions as drivers of hidradenitis suppurativa onset and progression. A holistic management approach addressing these factors may be encouraged to improve disease outcomes. Further research is needed to fully determine the causal role of these extrinsic factors and their impact on treatment strategies. ( J Am Acad Dermatol 2024;91:S17-21.)

引用

页码：S17 / S21

页数：5

共 50 条

[31] The critical role of macrophages in the pathogenesis of hidradenitis suppurativa
Shah, Ahmed
Alhusayen, Raed
Amini-Nik, Saeid
INFLAMMATION RESEARCH, 2017, 66 (11) : 931 - 945
[32] Molecular pathogenesis of hidradenitis suppurativa/acne inversa
Christos, C. Z.
Amir, M. H.
Nikolaos, B.
Daifallah, A.
Evgenia, M.
EXPERIMENTAL DERMATOLOGY, 2017, 26 : 10 - 10
[33] Factors associated with hidradenitis suppurativa severity
Schrader, Anne M. R.
Deckers, Inge E.
van der Zee, Hessel H.
Boer, Jurr
Prens, Errol P.
EXPERIMENTAL DERMATOLOGY, 2016, 25 : 8 - 8
[34] Dietary factors in patients with hidradenitis suppurativa
Ludwig, Catherine M.
Marr, Kendra D.
Mata, Elizabeth
Rivzi, Omar
Thompson, Alyssa
Hendricks, Aleksi J.
Maarouf, Melody
Fernandez, Jennifer M.
Price, Kyla N.
Hsiao, Jennifer
Shi, Vivian
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2020, 83 (06) : AB100 - AB100
[35] Involvement of the innate immune system in the hidradenitis suppurativa pathogenesis
Hue, Sophie
EXPERIMENTAL DERMATOLOGY, 2021, 30 : 46 - 46
[36] Reply to: "Hidradenitis suppurativa: Epidemiology, clinical presentation, and pathogenesis''
Stephan, Carla
Kurban, Mazen
Abbas, Ossama
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2020, 83 (05) : E371 - E371
[37] Complement activation in hidradenitis suppurativa: a new pathway of pathogenesis?
Kanni, T.
Zenker, O.
Habel, M.
Riedemann, N.
Giamarellos-Bourboulis, E. J.
BRITISH JOURNAL OF DERMATOLOGY, 2018, 179 (02) : 413 - 419
[38] Acne inversa/Hidradenitis suppurativa - From Pathogenesis to Therapy
Schuch, A.
Absmaier-Kijak, M.
Volz, T.
AKTUELLE DERMATOLOGIE, 2019, 45 (06) : 277 - 287
[39] Neutrophil trafficking: the missing link in the pathogenesis of hidradenitis suppurativa
Giamarellos-Bourboulis, E. J.
BRITISH JOURNAL OF DERMATOLOGY, 2021, 185 (01) : 15 - 16
[40] THE PATHOGENESIS OF HIDRADENITIS SUPPURATIVA IN MAN - EXPERIMENTAL AND HISTOLOGIC OBSERVATIONS
SHELLEY, WB
CAHN, MM
ARCHIVES OF DERMATOLOGY, 1955, 72 (06) : 562 - 565

← 1 2 3 4 5 →