Knowing when to stop: MICL self-regulates neutrophil NETosis

被引:0
|
作者
Shim, Hanjoo Brian [1 ,2 ]
Deniset, Justin Francois [1 ,2 ,3 ,4 ]
Kubes, Paul [1 ,2 ,5 ]
机构
[1] Univ Calgary, Dept Physiol & Pharmacol, Calgary, AB, Canada
[2] Univ Calgary, Calvin Phoebe & Joan Snyder Inst Chron Dis, Calgary, AB, Canada
[3] Univ Calgary, Dept Cardiac Sci, Calgary, AB, Canada
[4] Univ Calgary, Libin Cardiovasc Inst, Calgary, AB, Canada
[5] Queens Univ, Dept Biomed & Mol Sci, Kingston, ON, Canada
关键词
INFLAMMATION; CLEC12A;
D O I
10.1038/s41422-024-01037-9
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
In a recent study published inNature,Malamud et al.identified how neutrophil MICL recognizes neutrophil extra-cellular traps (NETs). This recognition suppresses furtherneutrophil activation and NET production, thereby preventinga vicious cycle of inflammation
引用
收藏
页码:89 / 90
页数:2
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