Knowing when to stop: MICL self-regulates neutrophil NETosis

被引：0
|
作者：
Shim, Hanjoo Brian [1 ,2 ]
Deniset, Justin Francois [1 ,2 ,3 ,4 ]
Kubes, Paul [1 ,2 ,5 ]
机构：
[1] Univ Calgary, Dept Physiol & Pharmacol, Calgary, AB, Canada
[2] Univ Calgary, Calvin Phoebe & Joan Snyder Inst Chron Dis, Calgary, AB, Canada
[3] Univ Calgary, Dept Cardiac Sci, Calgary, AB, Canada
[4] Univ Calgary, Libin Cardiovasc Inst, Calgary, AB, Canada
[5] Queens Univ, Dept Biomed & Mol Sci, Kingston, ON, Canada
来源：
CELL RESEARCH | 2025年 / 35卷 / 02期
关键词：
INFLAMMATION; CLEC12A;
D O I：
10.1038/s41422-024-01037-9
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
In a recent study published inNature,Malamud et al.identified how neutrophil MICL recognizes neutrophil extra-cellular traps (NETs). This recognition suppresses furtherneutrophil activation and NET production, thereby preventinga vicious cycle of inflammation
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页码：89 / 90
页数：2
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