Investigation of myocardial lipid peroxidation and myocardial enzyme activity under acute hypobaric hypoxia

被引：0
|
作者：
Li, Qingdi [1 ]
Yang, Ye [1 ]
Yu, Qifu [1 ]
Hao, Weiwei [1 ]
Qin, Suqing [1 ]
机构：
[1] Naval General Hospital, Beijing, China
来源：
Hangtian Yixue Yu Yixue Gongcheng/Space Medicine and Medical Engineering | 1994年 / 7卷 / 03期
关键词：
Enzyme kinetics - Free radicals - Lipids - Muscle - Oxygen - Peroxides - Tissue;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In this paper, SeGSHpx, MDA content, SeGSHpx/MDA ratio and several kinds of myocardial enzymes such as CPK, CK-MB, LDH, α-HBD and AST were measured in 39 healthy adult Wistar rats staying at 7500m for 30min in a hypobaric chamber in order to observe the effect of acute hypoxia upon the myocardium and the relationship between lipid peroxidation and myocardial damage. The results showed that activity of myocardial enzymes was raised significantly after acute hypoxia, the difference was remarkable as compared with the control values (P<0.01 or 0.001). Acute hypobaric hypoxia had also some influences on the myocardial SeGSHpx activity, MDA content, and SeGSHpx/MDA ratio.
引用
收藏
页码：181 / 185
相关论文
共 50 条
  • [31] GLUCOCORTICOID RESPONSE AND ADRENAL LIPID-PEROXIDATION IN RATS SUBMITTED TO CHRONIC HYPOBARIC HYPOXIA
    MARTIN, I
    AGUIRRE, F
    GROSMAN, G
    SARCHI, MI
    KOCH, O
    ARCHIVES INTERNATIONALES DE PHYSIOLOGIE DE BIOCHIMIE ET DE BIOPHYSIQUE, 1993, 101 (03): : 173 - 177
  • [32] Improvement of myocardial perfusion in coronary patients after intermittent hypobaric hypoxia
    Maria del Pilar Valle
    Félix García-Godos
    Orison O. Woolcott
    José M. Marticorena
    Víctor Rodríguez
    Isabel Gutiérrez
    Luis Fernández-Dávila
    Abel Contreras
    Luis Valdivia
    Juan Robles
    Emilio A. Marticorena
    Journal of Nuclear Cardiology, 2006, 13 : 69 - 74
  • [33] Improvement of myocardial perfusion in coronary patients after intermittent hypobaric hypoxia
    Valle, MD
    García-Godos, F
    Woolcott, OO
    Marticorena, JM
    Rodríguez, V
    Gutiérrez, I
    Fernández-Dávila, L
    Contreras, A
    Valdivia, L
    Robles, J
    Marticorena, EA
    JOURNAL OF NUCLEAR CARDIOLOGY, 2006, 13 (01) : 69 - 74
  • [34] Total antioxidant status, lipid parameters, lipid peroxidation and glutathione levels in patients with acute myocardial infarction
    Güler, K
    Palanduz, S
    Ademoglù, E
    Salmayenli, N
    Gökkusu, C
    Vatansever, S
    MEDICAL SCIENCE RESEARCH, 1998, 26 (02): : 105 - 106
  • [35] Plasma iron status and lipid peroxidation following thrombolytic therapy for acute myocardial infarction
    Cottin, Y
    Doise, JM
    Maupoil, V
    Tannière-Zeller, M
    Dalloz, F
    Maynadié, M
    Walker, MK
    Louis, P
    Carli, PM
    Wolf, JE
    Rochette, L
    FUNDAMENTAL & CLINICAL PHARMACOLOGY, 1998, 12 (02) : 236 - 241
  • [36] Effect of short term vitamin e supplementation on lipid peroxidation in acute myocardial infarction
    Jain A.P.
    Mohan A.
    Gupta O.P.
    Jajoo U.N.
    Kalantri S.P.
    Srivastava L.M.
    Indian Journal of Clinical Biochemistry, 1998, 13 (2) : 119 - 122
  • [37] Effect of intravenous Nitroglycerin on lipid peroxidation after thrombolytic therapy for acute myocardial infarction
    Öhlin, H
    Pavlidis, N
    Öhlin, AK
    AMERICAN JOURNAL OF CARDIOLOGY, 1998, 82 (12): : 1463 - 1467
  • [38] Effect of Shengmaisan（生脉散）on Lipid Peroxidation Damage in Acute Myocardial infarctionPatients
    吕宝经，荣烨之，赵美华，黄国芳，朱向阳，杨瑾文
    Chinese Journal of Integrated Traditional and Western Medicine , 1996, (04)
  • [39] MYOCARDIAL PROTEIN-SYNTHESIS IN ACUTE MYOCARDIAL HYPOXIA AND ISCHEMIA
    WOLLENBERGER, A
    ONNEN, K
    RABITZSCH, G
    HINTERBERGER, U
    KLEITKE, B
    CARDIOLOGY, 1971, 56 (01) : 48 - +
  • [40] ACTIVITY OF THE SUPEROXIDEDISMUTASE ENZYME AND METABOLITES OF LIPID-PEROXIDATION IN ACUTE INFLAMMATORY PROCESS
    FRANCHUK, AE
    BOICHUK, AV
    KUMPANENKO, VA
    SHARAPANOVSKAYA, EN
    VRACHEBNOE DELO, 1991, (09): : 95 - 96
12345